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Merck

01-6635

Sigma-Aldrich

氧化砷(III)

SAJ first grade, ≥99.0%

别名:

三氧化二砷, 亚砷酸

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About This Item

经验公式(希尔记法):
As2O3
CAS号:
分子量:
197.84
EC 号:
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:

等级

SAJ first grade

蒸汽压

0.000001 hPa ( 66 °C)

方案

≥99.0%

表单

powder

存货情况

available only in Japan

SMILES字符串

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

InChI key

IKWTVSLWAPBBKU-UHFFFAOYSA-N

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警示用语:

Danger

危险分类

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

靶器官

Respiratory system,Cardio-vascular system,Gastrointestinal tract

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yanfei Jia et al.
PloS one, 8(1), e54774-e54774 (2013-02-06)
Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC), represented by the production of AFP, has a more aggressive behavior than common gastric cancer. The underlying mechanisms are not well understood. Arsenic trioxide (As(2)O(3)) is used clinically to treat acute promyelocytic leukemia(APL) and has
Akio Iwanami et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(11), 4339-4344 (2013-02-27)
Despite their nearly universal activation of mammalian target of rapamycin (mTOR) signaling, glioblastomas (GBMs) are strikingly resistant to mTOR-targeted therapy. We analyzed GBM cell lines, patient-derived tumor cell cultures, and clinical samples from patients in phase 1 clinical trials, and
Jianing Wu et al.
Toxicology letters, 220(1), 61-69 (2013-04-02)
Notch signaling has been demonstrated to have a central role in cancer stem-like cells (CSLCs) in glioblastoma multiforme (GBM). We have recently demonstrated the inhibitory effect of arsenic trioxide (ATO) on CSLCs in glioblastoma cell lines. In this study we
Michael T Brady et al.
Leukemia research, 37(7), 822-828 (2013-05-01)
Signal transducer and activator of transcription (STAT) 3 inhibits dendritic cell (DC) differentiation and is constitutively activated in blasts of approximately half of AML patients. We investigated the correlation between STAT3 activity, DC maturation and the ability to stimulate T-cells
Y Zhang et al.
Neoplasma, 60(3), 247-253 (2013-02-05)
Arsenic trioxide (ATO) has been demonstrated to induce apoptosis in retinoblastoma cells, however, mechanisms responsible for this phenomenon are not fully understood. In the present study, we determined whether ATO induced apoptosis by abnormal expression of microRNA. In an apoptosis

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