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MADKMAG-71K

Millipore

MILLIPLEX®小鼠脂肪因子磁珠组套 - 内分泌多重检测试剂盒

The analytes available for this multiplex kit are: IL-6, Insulin, Leptin, MCP-1, PAI-1 (Total), Resistin, TNF-α.

别名:

luminex mouse adipokine multiplex kit, luminex mouse obesity multiplex kit, millipore mouse metabolic syndrome disease multiplex, mouse metabolism diabetes immunoassay panel

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.84

品質等級

200

物種活性

mouse

製造商／商標名

Milliplex®

assay range

accuracy: 77-92%
standard curve range: 12.2-50,000 pg/mL

技術

multiplexing: suitable

檢測方法

fluorometric (Luminex xMAP)

運輸包裝

wet ice

相关类别

一般說明

1994年发现脂肪细胞分泌瘦素导致人们认识到白色脂肪组织参与了多种代谢和生理过程。脂肪细胞分泌几种称为脂肪因子的激素，其功能包括食欲和能量平衡、胰岛素敏感性和脂质代谢。

MILLIPLEX®小鼠脂肪因子组套是一种7重试剂盒，用于同时定量小鼠血清和血浆样品中的以下任何或所有分析物：IL-6、胰岛素、瘦素、MCP-1、总PAI-1、抵抗素和TNFα。该试剂盒采用96孔板，包含冻干标准混合物、两个内部检测对照品，最多可测量38份样品，一式两份。

Luminex® xMAP®平台使用磁珠免疫分析格式，以实现理想的速度和灵敏度，同时定量多种分析物，从而显著提高生产力，同时节省有价值的样品量。

组套类型：代谢

特異性

交叉反应
组套中的每个抗体对均具有高度特异性，并且与组套中的其他分析物显示出微不足道的交叉反应性。

應用

  • 分析物：IL-6、胰岛素、瘦素、MCP-1（CCL2）、PAI-1（总计）、抵抗素、TNF-α
  • 建议样品类型：小鼠血清和血浆
  • 建议的样品稀释度：每孔10 μL未稀释的血清或血浆
  • 测定运行时间：在2-8°C下过夜（16-18小时）。
  • 研究类别：代谢
  • 研究子类别：内分泌、肥胖、代谢紊乱

特點和優勢

通过在此组套中选择可用的分析物来设计多重试剂盒。

其他說明

灵敏度：有关单个生物标志物的灵敏’度，请参见试剂盒方案。

法律資訊

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免責聲明

除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。

象形圖

Exclamation markEnvironment
GHS07,GHS09

訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

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Dimiter Avtanski et al.
Animal models and experimental medicine, 2(4), 252-258 (2020-01-17)
Animal models of diet-induced obesity (DIO) are commonly used in medical research for mimicking human diseases. There is no universal animal model, and careful evaluation of variety of factors needs to be considered when designing new experiments. Here, we investigated
Sara A DiVall et al.
PloS one, 10(3), e0119995-e0119995 (2015-03-18)
Infertility associated with obesity is characterized by abnormal hormone release from reproductive tissues in the hypothalamus, pituitary, and ovary. These tissues maintain insulin sensitivity upon peripheral insulin resistance. Insulin receptor signaling may play a role in the dysregulation of gonadotropin-releasing
Linda A Toth et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 54(6), 708-717 (2015-12-04)
To determine how housing density and ambient temperature interact to influence the physiology and behavior of mice, we systematically varied housing density (1 to 5 mice per cage) and ambient temperature (22, 26, or 30 °C) and measured effects on
Brandon D Kayser et al.
PloS one, 10(3), e0121954-e0121954 (2015-04-04)
Obesity causes white adipose tissue (WAT) inflammation and insulin resistance in some, but not all individuals. Here, we used a mouse model of early postnatal overfeeding to determine the role of neonatal nutrition in lifelong WAT inflammation and metabolic dysfunction.
Salman Azhar et al.
Molecular and cellular endocrinology, 480, 1-11 (2018-10-06)
Previously, apoE-derived ABCA1 agonist peptides have been shown to possess anti-atherosclerotic and possibly antidiabetic properties. Here we assessed the in vitro and in vivo actions of a second generation of ABCA1 peptide agonists, CS6253 and T6991-2, on glucose homeostasis. The
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