推荐产品
生物源
mouse
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
DP2.15, monoclonal
物種活性
bovine, human, chicken, rat, mouse
製造商／商標名
Chemicon®
技術
immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable
同型
IgG1
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... DSP(1832)
特異性
This antibody shows distinct punctate membrane staining of desmoplakins 1 (MW 250 kDa) and 2 (MW 215 kDa) in stratified epithelia and simple epithelia, including glands, urothelium, thymic reticular epithelium, hepatocytes, intercalated disks of myocardium and arachnoid cells of meninges.
免疫原
Bovine desmoplakin 1 & 2
應用
Anti-Desmoplakin 1& 2 Antibody, clone DP2.15 detects level of Desmoplakin 1& 2 & has been published & validated for use in IF, WB & IC.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Cytoskeleton
Cytoskeleton
Western blot
Immunohistochemistry: 1:10; Frozen tissue
Immunofluorescence
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: 1:10; Frozen tissue
Immunofluorescence
Optimal working dilutions must be determined by the end user.
外觀
Format: Purified
Lyophilized. Reconstitute in 1 mL distilled water (final solution contains 0.09% sodium
azide, 0.5% BSA in PBS buffer, pH 7.4
azide, 0.5% BSA in PBS buffer, pH 7.4
儲存和穩定性
Reconstituted antibody can be stored at 2°-8°C for up to 12 months from date of receipt. Antibody can also be stored at -20°C in undiluted aliquots.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Andrew Muroyama et al.
eLife, 6 (2017-09-05)
The physiological functions of microtubules (MTs) are poorly understood in many differentiated cell types. We developed a genetic toolkit to study MT dynamics and function in diverse cells. Using TRE-EB1-GFP mice, we found that MT dynamics are strongly suppressed in
Annika Gross et al.
Cellular and molecular gastroenterology and hepatology, 13(4), 1181-1200 (2021-12-21)
Desmosomes are intercellular junctions connecting keratin intermediate filaments of neighboring cells. The cadherins desmoglein 2 (Dsg2) and desmocollin 2 mediate cell-cell adhesion, whereas desmoplakin (Dsp) provides the attachment of desmosomes to keratins. Although the importance of the desmosome-keratin network is
Emily I Bartle et al.
The Journal of cell biology, 219(6) (2020-05-14)
Desmosomes are cell-cell junctions that provide mechanical integrity to epithelial and cardiac tissues. Desmosomes have two distinct adhesive states, calcium-dependent and hyperadhesive, which balance tissue plasticity and strength. A highly ordered array of cadherins in the adhesive interface is hypothesized
Wenxiu Ning et al.
Cell stem cell, 28(3), 436-452 (2020-12-03)
Basal stem cells fuel development, homeostasis, and regeneration of the epidermis. The proliferation and fate decisions of these cells are highly regulated by their microenvironment, including the basement membrane and underlying mesenchymal cells. Basal progenitors give rise to differentiated progeny
Chi-Hsiao Yeh et al.
International journal of molecular sciences, 22(21) (2021-11-14)
Aging is the major risk factor for cardiovascular disease, which is the leading cause of mortality worldwide among aging populations. Cisd2 is a prolongevity gene that mediates lifespan in mammals. Previously, our investigations revealed that a persistently high level of
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