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Merck
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Key Documents

BI0158

Sigma-Aldrich

Activator Reagent 0.5M ETT in Acetonitrile

0.5M ETT in Acetonitrile

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About This Item

分類程式碼代碼:
41116006

品質等級

200
300

產品線

Novabiochem®

形狀

liquid

反應適用性

reaction type: Coupling Reactions
reagent type: catalyst

轉變溫度

flash point 5.6 °C

運輸包裝

ambient

儲存溫度

2-30°C

應用

Ethyl thiotetrazole (ETT) in Acetonitrile can be used as an efficient activator reagent for the synthesis of oligonucleotides. This reagent is effective in the solid-phase synthesis of RNA oligonucleotides in terms of product yield in comparison with other reagents such as 4,5-dicyanoimidazole and 5-benzylthio-1H-tetrazole (BTT).

分析報告

Color (APHA): 10 max
ETT [5-(Ethylthio)-1H-tetrazole] Molarity: 0.48-0.52M
Form: Clear liquid
Water (H2O): 60ppm max

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

安全危害

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

42.1 °F

閃點(°C)

5.6 °C


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Stefanie Hoffmann et al.
Current protocols in nucleic acid chemistry, Chapter 4, Unit 4-Unit 4 (2011-09-09)
This unit describes the solid-phase synthesis and downstream processing for RNA oligonucleotides with a length of up to 40 to 50 nucleotides on a 1- to 4-mmol scale with subsequent conjugation to PEG using the L-RNA spiegelmer NOX-E36 as an

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