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Merck
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Key Documents

ABN642

Sigma-Aldrich

Anti-LRRTM1 Antibody

from rabbit, purified by affinity chromatography

别名:

Leucine-rich repeat transmembrane neuronal protein 1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

human, mouse

技術

immunohistochemistry: suitable
western blot: suitable

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... LRRTM1(679668)

一般說明

Leucine-rich repeat transmembrane neuronal protein 1 (LRRTM1) exhibits strong synaptogenic activity that is restricted to excitatory presynaptic differentiation that acts at both pre- and postsynaptic levels. LRRTMs are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM1 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.

免疫原

Epitope: C-terminus
KLH-conjugated synthetic peptide corresponding to the C-terminus of human LRRTM1.

應用

Anti-LRRTM1 Antibody detects level of LRRTM1 & has been published & validated for use in LRRTM1.
Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected LRRTM1 in human brain tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

品質

Evaluated by Western Blotting in mouse brain tissue lysate with and without blocking peptide.

Western Blotting Analysis: 1 μg/mL of this antibody detected LRRTM1 in mouse brain tissue lysate.

標靶描述

~70 kDa observed. Uncharacterized bands may be observed in some lysate(s).

外觀

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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