推荐产品
product name
STAT3抑制剂VI,S3I-201, STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription.
品質等級
化驗
≥95% (HPLC)
形狀
solid
製造商/商標名
Calbiochem®
儲存條件
OK to freeze
protect from light
顏色
light beige
溶解度
DMSO: 10 mg/mL (Use only fresh, anhydrous DMSO.)
運輸包裝
ambient
儲存溫度
−20°C
InChI
1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)
InChI 密鑰
HWNUSGNZBAISFM-UHFFFAOYSA-N
一般說明
一种细胞渗透性氨基水杨酸化合物,可结合Stat3-SH2结构域并阻止Stat3磷酸化/激活、二聚化、DNA结合和Stat3依赖性转录。显示在体外培养(有效浓度≤100 µM)和体内鼠异种移植模型(5 mg/kg,i.v.)中抑制Stat3依赖性肿瘤生长。也可以50 mM的DMSO溶液(目录号573130)提供。
包裝
用惰性气体包装
警告
毒性:监管审查(Z)
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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