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Merck
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Key Documents

573102

Sigma-Aldrich

S3I-201

≥95% (HPLC), solid, STAT3 inhibitor, Calbiochem®

别名:

STAT3抑制剂VI,S3I-201

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About This Item

经验公式(希尔记法):
C16H15NO7S
分子量:
365.36
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

product name

STAT3抑制剂VI,S3I-201, STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription.

品質等級

化驗

≥95% (HPLC)

形狀

solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
protect from light

顏色

light beige

溶解度

DMSO: 10 mg/mL (Use only fresh, anhydrous DMSO.)

運輸包裝

ambient

儲存溫度

−20°C

InChI

1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)

InChI 密鑰

HWNUSGNZBAISFM-UHFFFAOYSA-N

一般說明

一种细胞渗透性氨基水杨酸化合物,可结合Stat3-SH2结构域并阻止Stat3磷酸化/激活、二聚化、DNA结合和Stat3依赖性转录。显示在体外培养(有效浓度≤100 µM)和体内鼠异种移植模型(5 mg/kg,i.v.)中抑制Stat3依赖性肿瘤生长。也可以50 mM的DMSO溶液(目录号573130)提供。

包裝

用惰性气体包装

警告

毒性:监管审查(Z)

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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