565950

Sialyl Lewis x, Sodium Salt

Enzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins.

• 别名: Sialyl Lewis x, Sodium Salt, SLe ^x, Neu5Acα2,3Galβ1,4(Fucα1,3)GlcNAc, SLe^x, Neu5Acα2,3Galβ1,4(Fucα1,3)GlcNAc
• 经验公式（希尔记法）: C₃₁H₅₁N₂NaO₂₃
• CAS号: 98603-84-0
• 分子量: 842.73
• MDL號碼: MFCD00270073
• 分類程式碼代碼: 12352201
• NACRES: NA.79

属性

• 品質等級: 100
• 化驗: ≥95% (TLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: white
• 溶解度: water: 2 mg/mL
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• InChI: 1S/C31H52N2O23/c1-9-18(43)21(46)22(47)28(51-9)53-24(12(5-34)32-10(2)38)25(15(42)7-36)54-29-23(48)27(20(45)16(8-37)52-29)56-31(30(49)50)4-13(40)17(33-11(3)39)26(55-31)19(44)14(41)6-35/h5,9,12-29,35-37,40-48H,4,6-8H2,1-3H3,(H,32,38)(H,33,39)(H,49,50)/t9-,12-,13-,14+,15+,16+,17+,18+,19+,20-,21+,22-,23+,24+,25+,26+,27-,28-,29-,31-/m0/s1
• InChI 密鑰: LAQPKDLYOBZWBT-NYLDSJSYSA-N

说明

一般說明

Enzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins. SLe^x reduces injury following ischemia and reperfusion and immune complex-induced acute lung injury in animal models. In both of these models, SLe^x is presumed to act by blocking E-selectin-mediated neutrophil recruitment to sites of inflammation.

Enzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins. SLe^x reduces injury following ischemia, reperfusion and immune complex-induced acute lung injury in animal models. In both of these models, SLe^x is presumed to act by blocking E-selectin-mediated neutrophil recruitment to sites of inflammation.

警告

Toxicity: Standard Handling (A)

其他說明

Seekamp, A., et al. 1994. Am. J. Pathol.144, 592.
Mulligan, M.S., et al. 1993. J. Exp. Med.178, 623.
Ichikawa, Y., et al. 1992. J. Am. Chem. Soc. 114, 9283.
Lasky, L.A. 1992. Science 258, 964.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable