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219421

Sigma-Aldrich

Cathepsin L Inhibitor I

The Cathepsin L Inhibitor I, also referenced under CAS 108005-94-3, controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

别名:

Cathepsin L Inhibitor I, Z-FF-FMK

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About This Item

经验公式（希尔记法）:
C27H27FN2O4
CAS号:
108005-94-3
分子量:
462.51
MDL號碼:
MFCD24369030
分類程式碼代碼:
12352200
NACRES:
NA.77

品質等級

100

形狀

solid

製造商／商標名

Calbiochem®

儲存條件

OK to freeze
desiccated

顏色

white

溶解度

DMSO: 20 mM

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

FCC(=O)C(NC(=O)C(NC(=O)OCc3ccccc3)Cc2ccccc2)Cc1ccccc1

InChI

1S/C27H27FN2O4/c28-18-25(31)23(16-20-10-4-1-5-11-20)29-26(32)24(17-21-12-6-2-7-13-21)30-27(33)34-19-22-14-8-3-9-15-22/h1-15,23-24H,16-19H2,(H,29,32)(H,30,33)

InChI 密鑰

CAILNONEKASNSH-UHFFFAOYSA-N

一般說明

A potent, cell-permeable and irreversible inhibitor of cathepsin L.
A potent, cell-permeable, and irreversible inhibitor of Cathepsin L (Cat. No. 219402).

生化／生理作用

Cell permeable: yes
Primary Target
cathepsin L
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Standard Handling (A)

序列

Z-Phe-Phe-CH₂F

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

分析報告

single spot by TLC

其他說明

Ravanko, K., et al. 2004. Cancer Res.64, 8831.
Esser, R.E., et al. 1994. Arthritis Rheum. 37, 236.
Shaw, E., et al. 1993. FEBS Lett.334, 340.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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