06-1385
Anti-PDX1 (goat) Antibody
serum, from goat
别名:
pancreatic and duodenal homeobox 1, pancreatic-duodenal homeobox factor 1, somatostatin transcription factor 1, insulin promoter factor 1, homeodomain transcription factor, Insulin promoter factor 1, Somatostatin-transactivating factor 1, Insulin upstrea
登录查看公司和协议定价
所有图片(2)
About This Item
分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
推荐产品
生物源
goat
品質等級
抗體表格
serum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
human, mouse
技術
immunohistochemistry: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
mouse ... Pdx1(18609)
一般說明
Transcription factor PDX1, also known as pancreatic and duodenal homeobox 1, activates expression of the insulin and somatostatin genes. This protein is a key regulator of islet peptide hormone expression and also plays an essential role in pancreatic development. It has been shown to interact with the basic helix-loop-helix domains of TCF3(E47) and NEUROD1 and with HMG-I(Y). This protein also interacts with the methyltransferase SETD7. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus.
免疫原
Recombinant protein corresponding to the N-terminus of mouse PDX1.
應用
Anti-PDX1 (goat) Antibody is a Goat Polyclonal Antibody for detection of PDX1 also known as pancreatic & duodenal homeobox 1, somatostatin transcription factor 1, Insulin promoter factor 1 & has been validated in WB & IHC.
Immunohistochemistry Analysis: 1:400 dilution from a represenative lot detected PDX1 in normal human pancreas tissue.
品質
Evaluated by Western Blot in mouse pancreatic β T-cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected PDX1 on 10 µg of mouse pancreatic β T-cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected PDX1 on 10 µg of mouse pancreatic β T-cell lysate.
標靶描述
~ 39 kDa
外觀
Unpurified goat polyclonal serum containing 0.05% sodium azide.
未找到合适的产品？
试试我们的产品选型工具.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
Signaling pathways for sphingosylphosphorylcholine-mediated mitogenesis in Swiss 3T3 fibroblasts.
N N Desai,R O Carlson,M E Mattie,A Olivera,N E Buckley,T Seki,G Brooker,S Spiegel
The Journal of cell biology null
Romina J Bevacqua et al.
Nature communications, 12(1), 2397-2397 (2021-04-25)
Gene targeting studies in primary human islets could advance our understanding of mechanisms driving diabetes pathogenesis. Here, we demonstrate successful genome editing in primary human islets using clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein 9 (Cas9). CRISPR-based
Giannicola Genovese et al.
Nature, 542(7641), 362-366 (2017-02-09)
Malignant neoplasms evolve in response to changes in oncogenic signalling. Cancer cell plasticity in response to evolutionary pressures is fundamental to tumour progression and the development of therapeutic resistance. Here we determine the molecular and cellular mechanisms of cancer cell
Pauline Jeannot et al.
Oncotarget, 6(34), 35880-35892 (2015-09-30)
p27Kip1 (p27) is a negative regulator of proliferation and a tumor suppressor via the inhibition of cyclin-CDK activity in the nucleus. p27 is also involved in the regulation of other cellular processes, including transcription by acting as a transcriptional co-repressor.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门