推荐产品
生物源
mouse
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
GMA104, monoclonal
物種活性
human
製造商/商標名
Upstate®
技術
immunoprecipitation (IP): suitable
western blot: suitable
同型
IgG2a
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... AKT3(10000)
特異性
Predicted to cross-react with mouse and rat based on sequence homology.
RhoA
免疫原
peptide corresponding to amino acids 119-131 (CSPTSQIDNIGEE) of human Akt3/PKBγ
應用
Research Category
Signaling
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling
PI3K, Akt, & mTOR Signaling
This Anti-Akt3/PKBγ Antibody, clone GMA104 is validated for use in IP, WB for the detection of Akt3/PKBγ.
品質
routinely evaluated by immunoblot on RIPA lysates from Jurkat or HL-60 cells
標靶描述
~60kDa
外觀
Protein A purified
Buffered solution containing 0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4.
Format: Purified
儲存和穩定性
Stable for 1 year at 2-8°C from date of receipt.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
Cell communication and signaling : CCS, 22(1), 85-85 (2024-01-31)
K-Ras is the most frequently mutated Ras variant in pancreatic, colon and non-small cell lung adenocarcinoma. Activating mutations in K-Ras result in increased amounts of active Ras-GTP and subsequently a hyperactivation of effector proteins and downstream signaling pathways. Here, we
Biochemistry, 41(32), 10351-10359 (2002-08-07)
Protein kinase B (PKB), also known as Akt, is a serine/threonine protein kinase controlled by insulin, various growth factors, and phosphatidylinositol 3-kinase. Full activation of the PKB enzyme requires phosphorylation of a threonine in the activation loop and a serine
Oncotarget, 7(8), 9271-9287 (2016-01-30)
Despite multimodal therapies, a high percentage of high-risk neuroblastoma (NB) become refractory to current treatments, most of which interfere with cell cycle and DNA synthesis or function, activating the DNA damage response (DDR). In cancer, this process is frequently altered
The Akt isoforms are present at distinct subcellular locations.
American Journal of Physiology. Cell Physiology null
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