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Merck
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Key Documents

05-253MG

Sigma-Aldrich

Anti-ZAP-70 Antibody, clone 2F3.2

clone 2F3.2, Upstate®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

2F3.2, monoclonal

物種活性

human

製造商/商標名

Upstate®

技術

flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG2a

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ZAP70(7535)

一般說明

Note: This product is for research use only. It is not manufacured for diagnostic or therapeutic use in humans or animals.

特異性

human ZAP-70, does not recognize murine ZAP-70

免疫原

GST-fusion to tandem SH2 domains of human ZAP-70 corresponding to residues 1-254

應用

Detect ZAP-70 using this Anti-ZAP-70 Antibody, clone 2F3.2 validated for use in FC, IH, IP & WB.
Research Category
Signaling
Research Sub Category
Immunological Signaling

品質

routinely evaluated on RIPA lysates prepared from Jurkat cells or Hut-78 cell lysate

標靶描述

70kDa

外觀

Protein G Chromatography
Format: Purified
PBS

儲存和穩定性

2 years at -20°C

分析報告

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Marta Crespo et al.
The New England journal of medicine, 348(18), 1764-1775 (2003-05-02)
The mutational status of immunoglobulin heavy-chain variable-region (IgVH) genes in the leukemic cells of chronic lymphocytic leukemia (CLL) is an important prognostic factor in the disease. We investigated whether the expression of ZAP-70 by CLL cells correlated with the IgVH
TCR signaling: another Abl-bodied kinase joins the cascade.
Wange, Ronald L
Current Biology, 14, R562-R564 (2004)
D H Chu et al.
Immunological reviews, 165, 167-180 (1998-12-16)
The processes of T-cell development and activation employ similar immature and mature receptors as well as similar signal transduction pathways to achieve different outcomes. Many signaling molecules are shared between the receptor signaling pathways, including two families of cytoplasmic protein

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