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Key Documents

04-039

Sigma-Aldrich

Anti-20S proteasome subunit α2 Antibody, clone MCP21

clone MCP21, Upstate®, from mouse

别名:

HC3, proteasome subunit alpha type 2

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.28

生物源

mouse

品質等級

抗體表格

ascites fluid

抗體產品種類

primary antibodies

無性繁殖

MCP21, monoclonal

物種活性

human, rabbit, bovine

製造商/商標名

Upstate®

技術

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

基因資訊

bovine ... Psma2(539141)
human ... PSMA2(5683)
rabbit ... Psma2(100355295)

特異性

Recognizes proteasome subunit alpha type 2.

免疫原

Human placenta derived proteasomes

應用

Anti-20S proteasome subunit α2 Antibody, clone MCP21 detects level of 20S proteasome subunit α2 & has been published & validated for use in IP, WB, IH.
Research Category
Protein Trafficking
Research Sub Category
Ubiquitin & Ubiquitin Metabolism

標靶描述

26 kDa

外觀

Ascites
100 µL concentration of 1mg/mL purified ascites in PBS containing 0.01M sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.
Format: Purified

儲存和穩定性

Stable for 1 year at -20°C from date of shipment for up to 12 months.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Impact of ageing on proteasome structure and function in human lymphocytes
Carrard, Geraldine, et al
The International Journal of Biochemistry & Cell Biology, 35, 728-739 (2003)
Tomasz Klaus et al.
Scientific reports, 6, 30938-30938 (2016-08-04)
Mouse immunoglobulins M (IgMs) that recognize human blood group antigens induce haemagglutination and are used worldwide for diagnostic blood typing. Contrary to the current belief that IgGs are too small to simultaneously bind antigens on two different erythrocytes, we obtained
G Zhong et al.
The Journal of experimental medicine, 191(9), 1525-1534 (2000-05-03)
We have previously shown that the obligate intracellular pathogen chlamydia can suppress interferon (IFN)-gamma-inducible major histocompatibility complex (MHC) class II expression in infected cells by degrading upstream stimulation factor (USF)-1. We now report that chlamydia can also inhibit both constitutive
K B Hendil et al.
The Biochemical journal, 305 ( Pt 1), 245-252 (1995-01-01)
The proteasome or multicatalytic endopeptidase from eukaryotic cells consists of at least 14 subunits that fall into two families, alpha and beta. Subunit-specific monoclonal antibodies against ten different subunits of human proteasomes have been produced, together with an antibody that
Tomasz Klaus et al.
Frontiers in immunology, 9, 1096-1096 (2018-06-08)
Mouse IgG3 is highly protective against several life-threatening bacteria. This isotype is the only one among mouse IgGs that forms non-covalent oligomers, has increased functional affinity to polyvalent antigens, and efficiently agglutinates erythrocytes. IgG3 also triggers the complement cascade. The

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