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Merck

B-043

Supelco

Brompheniramine maleate solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式(希尔记法):
C20H23BrN2O4
CAS号:
分子量:
435.31
EC 号:
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material

表单

liquid

特点

SNAP-N-SPIKE®, SNAP-N-SHOOT®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

浓度

1.0 mg/mL in methanol (as free base)

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

pharmaceutical (small molecule)

包装形式

single component solution

储存温度

−20°C

SMILES字符串

OC(=O)\C=C/C(O)=O.CN(C)CCC(c1ccc(Br)cc1)c2ccccn2

InChI

1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

SRGKFVAASLQVBO-BTJKTKAUSA-N

基因信息

human ... HRH1(3269)

一般描述

Brompheniramine is an over-the-counter antihistamine sold under the trade names Bromfed®, Dimetapp®, and Lodrane®. The drug is indicated for treatment of the common cold and allergic rhinitis symptoms including runny nose and itchy eyes. This Snap-N-Spike® Reference Solution is suitable for use as starting material in calibrators or controls for LC/MS or GC/MS methods in clinical toxicology, forensic analysis, and pharmaceutical research.

法律信息

Bromfed is a registered trademark of Wockhardt EU Operations Swiss AG
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Dimetapp is a registered trademark of Wyeth LLC
Lodrane is a registered trademark of ECR Pharmaceuticals Co., Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ahmed S Zidan et al.
Journal of pharmaceutical sciences, 101(4), 1450-1461 (2012-01-04)
The objective of the current study was to evaluate the performance of Raman and near-infrared (NIR) techniques combined with chemometrics in characterizing the critical quality attributes of brompheniramine (BP)-tannate complexes. Seven complexes were prepared and evaluated for chemical interactions, solubilities
Rachel Walsh et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(30), 3523-3530 (2011-10-11)
A novel non-stabilised aqueous suspension polymerisation methodology for the preparation of spherical molecularly imprinted polymers is described with chlorpheniramine (CP), d-chlorpheniramine (d-CP), brompheniramine (BP) and d-brompheniramine (d-BP) as the templates, respectively. Using this rapid and simple technique, controlled polymer beads
Silvia Tardioli et al.
The journal of physical chemistry. B, 116(24), 7033-7039 (2012-05-23)
Binding of the antihistamine drug brompheniramine (BPA) to human serum albumin (HSA) is studied by measuring quenching of the fluorescence and room temperature phosphorescence (RTP) of tryptophan. The modified Stern-Volmer equation was used to derive association constants and accessible fractions
Laura R Sadofsky et al.
Experimental lung research, 34(10), 681-693 (2008-12-17)
American guidelines, unlike European guidelines, support the use of antihistamines as a first line of treatment for some causes of chronic cough. Transient receptor potential vanilloid-1 (TRPV1) is an ion channel activated by the tussive agents capsaicin, resiniferatoxin, and protons.
Ana Carolina Valinoti et al.
Journal of applied oral science : revista FOB, 16(4), 257-265 (2008-12-18)
This study evaluated the effects of acidic medicines (Dimetapp and Claritin), under pH-cycling conditions, on the surface degradation of four composite resins (microhybrid: TPH, Concept, Opallis and Nanofilled: Supreme). Thirty disc-shaped specimens ([symbol: see text] = 5.0 mm/thickness = 2.0

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