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文件

880135P

Avanti

DSPE-PEG (2000) 羧酸

Avanti Research™ - A Croda Brand 880135P, powder

别名:

1,2-二硬脂酰-sn-甘油-3-磷酸乙醇胺-N-[羧基(聚乙二醇)-2000] (钠盐)

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About This Item

经验公式（希尔记法）:
C131H257NNaO55P
CAS号:
1403744-37-5
分子量:
2780.38
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 10 mg (880135P-10mg)
pkg of 1 × 100 mg (880135P-100mg)
pkg of 1 × 25 mg (880135P-25mg)
pkg of 1 × 50 mg (880135P-50mg)
pkg of 1 × 500 mg (880135P-500mg)

製造商／商標名

Avanti Research™ - A Croda Brand 880135P

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OCCNC(C/C=C\OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOCCOOCC(O)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=

相关类别

一般說明

羧酸易溶于水和乙醇等极性溶剂。DSPE-PEG（2000）羧酸由2kDa的亲水性聚乙二醇（PEG）链组成。

應用

DSPE-PEG（2000）羧酸用于：
  • 将整联蛋白 α-2（ITGA2）抗体共价结合至脂质体表面
  • 制备阿托西班结合的脂质体
  • 制备双重互补脂质体

生化／生理作用

DSPE-PEG（2000）羧酸增加脂质体的血液循环时间。DSPE-PEG（2000）羧酸的羧基有助于和抗体共价结合。

包裝

20 mL 透明玻璃螺旋盖小瓶 (880135P-500 mg)
5 mL 棕色玻璃螺旋盖小瓶 (880135P-10 mg)
5 mL 棕色玻璃螺旋盖小瓶 (880135P-100 mg)
5 mL 棕色玻璃螺旋盖小瓶 (880135P-25 mg)
5 mL 棕色玻璃螺旋盖小瓶 (880135P-50 mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

No data available

閃點（°C）

No data available

分析证书(COA)

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Carboxylic Acid: Key Role in Life Sciences (2019)
ITGA2 as a potential nanotherapeutic target for glioblastoma
Guo P, et al.
Scientific reports, 9(1), 6195-6195 (2019)
Mohammad Mashreghi et al.
Nanoscale research letters, 15(1), 101-101 (2020-05-10)
In this study, we have surface-functionalized PEGylated-nanoliposomal doxorubicin (DOX) with anti-EpCAM (epithelial cell adhesion molecule) aptamer via post-insertion of anti-EpCAM aptamer-conjugated DSPE-mPEG2000 into Caelyx® (ED-lip). The size, charge, release profile, and cytotoxicity and cellular uptake of formulation were determined. The
Junxue An et al.
Journal of colloid and interface science, 577, 92-100 (2020-05-31)
Phospholipids constitute biocompatible and safe excipients for pulmonary drug delivery. They can retard the drug release and, when PEGylated, also prolong the residence time in the lung. The aim of this work was to assess the structure and coherence of
Feifei Yang et al.
Small (Weinheim an der Bergstrasse, Germany), 16(7), e1906360-e1906360 (2020-01-24)
Hepatotoxicity is a key concern in the clinical translation of nanotherapeutics because preclinical studies have consistently shown that nanotherapeutics accumulates extensively in the liver. However, clinical-stage nanotherapeutics have not shown increased hepatotoxicity. Factors that can contribute to the hepatotoxicity of
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