880120C

18:0 PEG2000 PE

Avanti Research^™ - A Croda Brand 880120C

• 别名: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)
• CAS号: 474922-77-5
• UNSPSC代码: 12352211
• NACRES: NA.25

属性

• 表单: liquid
• 包装: pkg of 1 × 2.5 mL (880120C-25mg); pkg of 1 × 20 mL (880120C-500mg); pkg of 2 × 4 mL (880120C-200mg)
• 制造商/商品名称: Avanti Research^™ - A Croda Brand 880120C
• 浓度: 10 mg/mL (880120C-25mg); 25 mg/mL (880120C-200mg); 25 mg/mL (880120C-500mg)
• 运输: dry ice
• 储存温度: −20°C
• SMILES字符串: [H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]
• InChI: 1S/C133H264NO55P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-131(135)186-128-130(189-132(136)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2)129-188-190(138,139)187-37-36-134-133(137)185-127-126-184-125-124-183-123-122-182-121-120-181-119-118-180-1
• InChI key: QSWJINHFEMDVEM-OJCMNYADSA-N

说明

一般描述

18:0 PEG2000 PE, also known as 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000], is a modified phospholipid containing a 2000-Da PEG moiety in the polar head.[1]

应用

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium salt (DSPE-PEG1) has been used to conjugate PEG onto residual amine groups on the surfaces of the functionalized TaO nanoparticles.[2] DSPE-PEG1 may be used as a surfactant for homeotropic anchoring of the mesogen molecules.[1] It may also be used in preparation of Nano formulations.[3]

生化/生理作用

PEG-modified lipids are typically added to phospholipid vesicles used for drug delivery to facilitate the formation of sterically stabilized liposomes (SSL). These liposomes have low reticuloendothelial system (RES) uptake and they prolong the circulating plasma half-life of the drug. The plasma half-life of the drug can be tuned from several hours to days depending on the size of the PEG and fatty acids attached to the lipid anchor.[4]

包装

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (880120C-500mg)

5 mL Clear Glass Sealed Ampule (880120C-200mg)

5 mL Clear Glass Sealed Ampule (880120C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 象形图: GHS06,GHS08
• 警示用语：: Danger
• 危险声明: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• 预防措施声明: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• 危险分类: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• 靶器官: Central nervous system, Liver,Kidney
• 储存分类代码: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• 闪点(°F): does not flash
• 闪点(°C): does not flash