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Merck

T30805

Sigma-Aldrich

硫代醋酸

96%

别名:

TAA, TMA, 硫代乙酸

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About This Item

线性分子式:
CH3COSH
CAS号:
分子量:
76.12
Beilstein:
1733298
EC 号:
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

96%

折射率

n20/D 1.465 (lit.)

沸点

88-91.5 °C (lit.)

密度

1.065 g/mL at 25 °C (lit.)

储存温度

2-8°C

SMILES字符串

CC(S)=O

InChI

1S/C2H4OS/c1-2(3)4/h1H3,(H,3,4)

InChI key

DUYAAUVXQSMXQP-UHFFFAOYSA-N

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应用

硫代乙酸 (TAA) 可在新型亚磺酰基脲有机催化剂存在下,与硝基烯烃发生
  • 对映体选择性加成,形成手性 1,2-氨基硫醇衍生物。该方法已成功地用于抗真菌药物硫康唑的合成。
  • 双官能团胺硫脲催化不对称 Michael 加成反应,生成硫酯。
  • 不对称 1,6-共轭加成反应 对位 -醌甲烷在手性磷酸催化剂存在下生成手性含硫二苯基甲烷型化合物。
  • 甲基丙烯酰胺与手性反式-2,5-二取代吡咯烷助剂的共轭加成形成手性 β-巯基羧酸衍生物。

硫代乙酸是将巯基引入有机分子的试剂。

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2 - Skin Sens. 1

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

64.4 °F - closed cup

闪点(°C)

18 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Dong N, et al.
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