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Merck

L5632

Sigma-Aldrich

羽扇豆醇

≥94%

别名:

20(29)-羽扇烯-3β-醇, 3β-羟基-20(29)-羽扇烯, 羽扇豆醇, 羽扇豆醇酯, 羽扇醇, 蛇麻醇酯

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About This Item

经验公式(希尔记法):
C30H50O
CAS号:
分子量:
426.72
EC 号:
MDL编号:
UNSPSC代码:
12352002
PubChem化学物质编号:
NACRES:
NA.22
价格与库存信息目前不能提供

质量水平

方案

≥94% (TLC)
≥94%

储存温度

2-8°C

SMILES字符串

[H]C12CCC3C4(C)CCC(O)C(C)(C)[C@]4([H])CCC3(C)[C@]1(C)CCC5(C)CC[C@H](C(C)=C)[C@]25[H]

InChI

1S/C30H50O/c1-19(2)20-11-14-27(5)17-18-29(7)21(25(20)27)9-10-23-28(6)15-13-24(31)26(3,4)22(28)12-16-30(23,29)8/h20-25,31H,1,9-18H2,2-8H3/t20-,21+,22-,23+,24-,25+,27+,28-,29+,30+/m0/s1

InChI key

MQYXUWHLBZFQQO-QGTGJCAVSA-N

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一般描述

羽扇豆醇是一种饮食来源的新型抗癌和抗炎三萜。它有助于稳定植物细胞膜的磷脂双层结构。通常,该基团含有28-29个碳以及碳-碳双键,通常有一个位于甾醇核中,有时会有另一个位于烷基侧链中。[1]

应用

羽扇豆醇已被用作参考标准品,用于开发和验证检测夜香牛(Vernonia Cinerea)中的羽扇豆醇的HPLC法。[2] 它已被用作标准品,用于通过GC鉴定和定量蓝莓角质层蜡质中的三萜类化合物。[3]

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Fruit characteristics and cuticle triterpenes as related to postharvest quality of highbush blueberries.
Moggia C, et al.
Sci. Hortic., 211, 449-457 (2016)
Shuang Liang et al.
Journal of natural products, 73(4), 532-535 (2010-03-03)
Phytochemical examination of the methanolic extract from the stem bark of Daphne aurantiaca led to the isolation of six new sesquiterpenoids, dauca-3,11-dien-2alpha,15-diol (1), 3-oxoguai-4-ene-11,12-diol (2), 4alpha,5alpha,8alpha,11alphaH-3-oxoguai-1(10)-en-12,8-olide-7alpha-diol (3), 4alpha,5alpha,8alpha,11betaH-3-oxoguai-1(10)-en-12,8-olide-7beta-diol (4), 4alpha,5betaH-guai-9,7(11)-dien-12,8-olide-1alpha,8alpha-diol (5), 4alpha,5alphaH-guai-9,7(11)-dien-12,8-olide-1alpha,8alpha-diol (6), and a new diterpenoid, 12-O-benzoylphorbol 13-nonanoate (7)
Development and validation of High Performance Liquid Chromatographic Method for the Simultaneous Determination of ?-sitosterol and Lupeol in Veronica cinerea Linn.
Shah, Willy, M. B. Kekare, and Vikas Vaidya.
International Journal of Pharma and Bio Sciences, 1 (3), 1-5 (2010)
Hifzur Rahman Siddique et al.
Life sciences, 88(7-8), 285-293 (2010-12-02)
Since ancient times, natural products have been used as remedies to treat human diseases. Lupeol, a phytosterol and triterpene, is widely found in edible fruits, and vegetables. Extensive research over the last three decades has revealed several important pharmacological activities
Archana Kumari et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(5), 1781-1789 (2012-03-13)
Drug induced hepatotoxicity is a major problem where phytochemicals hold promise for its abrogation. This study was carried out to explore cytoprotective potential of lupeol, a triterpene, against acetaminophen (AAP)-induced toxicity in rat hepatocytes. AAP exposure significantly (p<0.05) reduced cell

Questions

  1. what is the solubility of lupeol in DMSO? How can I make 50 micromolar solutions of lupeol?

    1 answer
    1. The solubility of Lupeol in DMSO is 3 mg/mL ( (7.03 mM). Moisture-absorbing DMSO reduces solubility therefore it is important to use fresh DMSO.
      50 micromoles = 0.00005 moles
      1 mole of Lupeol contains 426.72g, therefore 0.00005 moles contain (0.00005 moles/1mole) * 426.72g/mol) = 21.336mg
      Thus, dissolving 21.336mg of Lupeol in 1 Liter of DMSO will yield a 50 micromolar solution of Lupeol.

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