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Merck

ALD00500

Sigma-Aldrich

5-Methoxy-1,2,3-triazine

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About This Item

经验公式(希尔记法):
C4H5N3O
分子量:
111.10
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

形狀

powder

品質等級

儲存溫度

2-8°C

SMILES 字串

COC1=CN=NN=C1

InChI

1S/C4H5N3O/c1-8-4-2-5-7-6-3-4/h2-3H,1H3

InChI 密鑰

HVBZCUMRMKODNE-UHFFFAOYSA-N

一般說明

5-Methoxy-1,2,3-triazine is a 1,2,3-triazine derivative bearing electron-donating substituent. It participates in the inverse electron demand Diels-Alder reactions. 5-Methoxy-1,2,3-triazine readily reacts with amidines. It can be prepared from 4-methoxypyrazole.

應用

1, 2, 3-Triazines have shown to be reactive substrates in inverse electron demand Diels-Alder strategies. Recent examples by Boger and coworkers utilize this reactive motif in the construction of highly functionalized N-containing heterocycles.
5-Methoxy-1,2,3-triazine may be used in the synthesis of nitrogen-containing heterocyclic compounds.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Christopher M Glinkerman et al.
Organic letters, 17(16), 4002-4005 (2015-07-15)
The examination of the cycloaddition reactions of 1,2,3-triazines 17-19, bearing electron-donating substituents at C5, are described. Despite the noncomplementary 1,2,3-triazine C5 substituents, amidines were found to undergo a powerful cycloaddition to provide 2,5-disubstituted pyrimidines in excellent yields (42-99%; EDG =

商品

Inverse electron demand Diels-Alder reactions enable total synthesis of natural products with heteroaromatic ring systems.

Inverse electron demand Diels-Alder reactions enable total synthesis of natural products with heteroaromatic ring systems.

Inverse electron demand Diels-Alder reactions enable total synthesis of natural products with heteroaromatic ring systems.

Inverse electron demand Diels-Alder reactions enable total synthesis of natural products with heteroaromatic ring systems.

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Boger Lab utilizes nature's solutions in complex natural products, extending them through rational design for improved biological outcomes.

Boger Lab utilizes nature's solutions in complex natural products, extending them through rational design for improved biological outcomes.

Boger Lab utilizes nature's solutions in complex natural products, extending them through rational design for improved biological outcomes.

Boger Lab utilizes nature's solutions in complex natural products, extending them through rational design for improved biological outcomes.

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