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應用
S-(Trifluoromethyl)thianthrenium triflate (TT-CF3+ OTf-) is a trifluoromethylation reagent active for a diverse substrate range. Developed by the Ritter Lab, the enchanced activity is accomplished by participation in either nucleophilic, radical, or electrophilic mechanisms depending on the selected reaction conditions, allowing for the introduction of trifluoromethyl moieties to many substrates with a high functional group tolerance.
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法律資訊
Patent application: EP21169034.2
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Journal of the American Chemical Society, 143(20), 7623-7628 (2021-05-15)
Here we report the synthesis and application of trifluoromethyl thianthrenium triflate (TT-CF3+OTf-) as a novel trifluoromethylating reagent, which is conveniently accessible in a single step from thianthrene and triflic anhydride. We demonstrate the use of TT-CF3+OTf- in electrophilic, radical, and
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