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Merck

918970

Sigma-Aldrich

VincePhos

≥95%

别名:

7,7,9,9-Tetramethyl-8-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)-1,4-dioxa-8-phosphaspiro[4.5]decane

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About This Item

经验公式(希尔记法):
C34H51O4P
分子量:
554.74
分類程式碼代碼:
12352112
NACRES:
NA.22

品質等級

化驗

≥95%

形狀

powder

反應適用性

reagent type: catalyst
reaction type: Cross Couplings

reagent type: ligand

官能基

phosphine

儲存溫度

−20°C

應用

VincePhos is a biaryl phosphorinane ligand for Pd catalysis. This ligand has been used in a variety of Pd-catalyzed reactions including the sulfonamidation of aryl halides, C-O couplings, and C-N couplings.

相關產品

产品编号
说明
价格

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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David M Barnes et al.
The Journal of organic chemistry, 84(8), 4873-4892 (2019-01-11)
Dasabuvir (1) is an HCV polymerase inhibitor which has been developed as a part of a three-component direct-acting antiviral combination therapy. During the course of the development of the synthetic route, two novel coupling reactions were developed. First, the copper-catalyzed
Pd-Catalyzed Cross-Coupling Reactions Promoted by Biaryl Phosphorinane Ligands.
Laffoon S D, et al.
ACS Catalysis, 9(12), 11691-11708 (2019)

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