900605

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• 别名: Bromo sulfonyl fluoride alkyne, Probe building block
• 经验公式（希尔记法）: C₁₂H₁₄BrFO₂SSi
• CAS号: 2088829-12-1
• 分子量: 349.29
• MDL编号: MFCD30737997
• UNSPSC代码: 12352200
• NACRES: NA.22

属性

• 质量水平: 100
• 方案: ≥95%
• 表单: solid
• 反应适用性: reaction type: click chemistry
• 储存温度: −20°C
• SMILES字符串: [Si](C)(C)(C)C#Cc1cc(cc(c1)CBr)[S](=O)(=O)F
• InChI: 1S/C12H14BrFO2SSi/c1-18(2,3)5-4-10-6-11(9-13)8-12(7-10)17(14,15)16/h6-8H,9H2,1-3H3
• InChI key: QSYGHPYMWBAJRL-UHFFFAOYSA-N

说明

应用

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

其他说明

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable