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形狀
liquid
品質等級
儲存溫度
2-8°C
SMILES 字串
F/O=C1N(C)CCCN\1C
InChI
1S/C6H12FN2O/c1-8-4-3-5-9(2)6(8)10-7/h3-5H2,1-2H3
InChI 密鑰
ZTQIVQDBIIEDTI-UHFFFAOYSA-N
應用
DMPU-HF试剂是一种亲核氟化试剂，可用于：
- 在Au-JohnPhos配合物催化下将取代炔烃制备为氟代烯烃和gem-二氟甲烯。
- 通过氟化-Prins反应用高烯丙醇/胺和醛合成取代4-氟四氢吡喃类和4-氟哌啶类化合物。
- 在N-溴代琥珀酰亚胺的存在下通过炔烃的溴氟化反应生产相应的溴氟化化合物。
与TREAT-HF 和 Olah 试剂类似，DMPU-HF是将氟化氢用作氟化试剂的简便方法。但与 TREAT-HF 和 Olah 试剂不同的是：同三乙胺和吡啶相比，由于 DMPU 的碱度降低，DMPU-HF 对过渡金属的耐受性更强。Hammond 及其同事在金催化的炔烃单和双氟化反应中展示了其在过渡金属催化中的兼容性。
訊號詞
Danger
危險分類
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Skin Corr. 1A
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Shengzong Liang et al.
Journal of fluorine chemistry, 203, 136-139 (2018-02-13)
Bromofluorination reactions were performed by treating of a variety of unsaturated compounds with N-bromosuccinimide (NBS) and DMPU/HF as the fluorinating reagent. The DMPU/HF complex showed to be an efficient fluorinating reagent to convert alkenes into their corresponding bromofluoro compounds. It
Otome E Okoromoba et al.
Journal of the American Chemical Society, 136(41), 14381-14384 (2014-09-27)
Hydrogen fluoride (HF) and selected nonbasic and weakly coordinating (toward cationic metal) hydrogen-bond acceptors (e.g., DMPU) can form stable complexes through hydrogen bonding. The DMPU/HF complex is a new nucleophilic fluorination reagent that has high acidity and is compatible with
Otome E Okoromoba et al.
Organic letters, 17(16), 3975-3977 (2015-08-12)
DMPU/HF (HF content 65 wt %/wt) is an ideal nucleophilic fluorination reagent for the diastereoselective synthesis of substituted 4-fluorotetrahydropyrans and 4-fluoropiperidines via a fluoro-Prins reaction. When compared to classical nucleophilic fluorination reagents like pyridine/HF, DMPU/HF gives both higher yields and
相关内容
The research of the Hammond-Xu Group is focused on the understanding of novel interactions between organic and organometallic compounds from the perspective of physical organic chemistry.
The research of the Hammond-Xu Group is focused on the understanding of novel interactions between organic and organometallic compounds from the perspective of physical organic chemistry.
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