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Merck

779229

Sigma-Aldrich

(2-羟丙基)-γ-环糊精

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science

别名:

Cavasol® W8 HP, HGC

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About This Item

分類程式碼代碼:
12352201
NACRES:
NA.22

等級

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science

品質等級

形狀

powder

標籤範圍

0.5-0.7 molar substitution

雜質

≤0.1% propylene glycol (Ph Eur)

損耗

≤10.0% loss on drying

pH值

6-9 (2% in H2O)

InChI

1S/C51H88O38/c1-14(56)8-73-11-21-42-29(64)36(71)50(81-21)85-40-19(6-54)79-48(34(69)27(40)62)89-44-23(13-75-10-16(3)58)82-51(37(72)30(44)65)86-41-20(7-55)78-47(33(68)26(41)61)88-43-22(12-74-9-15(2)57)80-49(35(70)28(43)63)84-39-18(5-53)76-45(31(66)24(39)59)83-38-17(4-52)77-46(87-42)32(67)25(38)60/h14-72H,4-13H2,1-3H3/t14?,15?,16?,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-/m0/s1

InChI 密鑰

ODLHGICHYURWBS-RYJYQAAZSA-N

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一般說明

(2-羟丙基)--γ环糊精(HP-β-CD)是一种亲水性化合物,可作为络合剂增加药物分子的水溶性和溶解速率。

應用

HP-β-CD可用于提高络合时唑吡坦(ZP)的水溶性和溶解速率。ZP-HP-β-CD络合物显示出改善的无秩序活性。
它还用于通过增加水溶性来增强姜黄素的伤口愈合性能。
仅供R&D使用

法律資訊

Cavasol is a registered trademark of Wacker Chemie AG

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Enhancement of curcumin wound healing ability by complexation with 2-hydroxypropyl-γ-cyclodextrin in sacran hydrogel film
Wathoni N, et al.
International Journal of Biological Macromolecules, 98(11), 268-276 (2017)
Complexation of Zolpidem with 2-hydroxypropyl-β -, methyl-β -, and 2-hydroxypropyl-γ -cyclodextrin: Effect on aqueous solubility, dissolution rate, and ataxic activity in rat
Trapani, G, et al.
Journal of Pharmaceutical Sciences, 89(11), 1443-1451 (2000)
Physicochemical study and characterization of the trimethoprim/2-hydroxypropyl-γ -cyclodextrin inclusion complex
Macedo OFL, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 86(11), 101-106 (2012)
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The European journal of neuroscience, 30(3), 493-503 (2009-08-07)
The orexin/hypocretin system has recently been implicated in reward-processing and addiction. We examined the involvement of the orexin system in cue-induced reinstatement of extinguished cocaine-seeking by administering the orexin 1 receptor antagonist SB-334867 (SB) or the orexin 2 receptor antagonist
D E Rusyniak et al.
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