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Merck

524980

Sigma-Aldrich

邻苯二甲酸二丁酯(驱蚊叮)

Dibutyl phthalate

99%

别名:

DBP, 正丁基邻苯二甲酸酯, 邻苯二甲酸二丁基酯

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About This Item

线性分子式:
C6H4-1,2-[CO2(CH2)3CH3]2
CAS号:
分子量:
278.34
Beilstein:
1914064
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
价格与库存信息目前不能提供

蒸汽密度

9.6 (vs air)

质量水平

蒸汽压

1 mmHg ( 147 °C)

方案

99%

表单

liquid

自燃温度

756 °F

expl. lim.

0.47 %, 236 °F

杂质

≤0.005% Acidity (as Phthalic acid)
≤0.15% water

颜色

APHA: ≤20

折射率

n20/D 1.492 (lit.)

pH值(酸碱度)

7 (20 °C, 10 mg/L)

沸点

340 °C (lit.)

mp

−35 °C (lit.)

密度

1.043 g/mL at 25 °C (lit.)

官能团

ester

SMILES字符串

CCCCOC(=O)c1ccccc1C(=O)OCCCC

InChI

1S/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3

InChI key

DOIRQSBPFJWKBE-UHFFFAOYSA-N

基因信息

mouse ... Esr1(13982)

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一般描述

邻苯二甲酸二丁酯(DBP)最常用作各种家用产品中的增塑剂。在使用或处理这些产品时,它可以浸出和蒸发到环境中。[1][2]因此,针对其毒性和细胞凋亡效应的研究正在进行。[1]研究还表明,接触高剂量的DBP可能会干扰黄体酮和雌二醇的产生。[2]

应用

增塑剂

象形图

Health hazardEnvironment

警示用语:

Danger

危险声明

危险分类

Aquatic Acute 1 - Aquatic Chronic 2 - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

367.7 °F - open cup

闪点(°C)

186.5 °C - open cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Dibutyl phthalate impairs steroidogenesis and a subset of LH-dependent genes in cultured human mural granulosa cell in vitro.
Adir M
Reproductive Toxicology, 69, 13-18 (2017)
Dibutyl phthalate (DBP)-induced apoptosis and neurotoxicity are mediated via the aryl hydrocarbon receptor (AhR) but not by estrogen receptor alpha (ER?), estrogen receptor beta (ER?), or peroxisome proliferator-activated receptor gamma (PPAR?) in mouse cortical neurons.
Wojtowicz A
Neurotoxicity Research, 31(1), 77-89 (2017)
Damien Hunter et al.
International journal of molecular sciences, 22(8) (2021-05-01)
Xenobiotic exposure during pregnancy and lactation has been linked to perinatal changes in male reproductive outcomes and other endocrine parameters. This pilot study wished to assess whether brief maternal exposure of rats to xenobiotics dibutyl phthalate (DBP) or diethylstilbestrol (DES)
Linda V Sinclair et al.
Immunometabolism, 2(4), e200029-e200029 (2020-09-04)
Assays to monitor the metabolic state or nutrient uptake capacity of immune cells at a single cell level are increasingly in demand. One assay, used by many immunologists, employs 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG), a fluorescent analogue of 2-deoxyglucose (2DG), as a substrate
Harpreet Bhatia et al.
Aquatic toxicology (Amsterdam, Netherlands), 149, 103-115 (2014-03-01)
Phthalic acid esters (PAEs) are a class of synthetic industrial chemicals commonly found in the aquatic environment worldwide. PAEs have been recognised as anti-androgens in male mammals but little is known about their endocrine disrupting effects in fish. This study

Questions

1–4 of 4 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. En que esta disuelto? a que concentración?

    1 answer
    1. This item is in liquid form with a purity of greater than or equal to 99.0%; it is not mixed with anything. Please see the sample Certificate of Anaylsis here: https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/524980-BULKMKCV6253.pdf

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  4. Buenos días, Me gustaría confirmar si el formato "poly bottle" se trata de una botella de plástico y en su caso, si existe algún tipo de diferencia entre los formatos de 25 y 100 mL, puesto que la diferencia de precio es mínima.

    1 answer
    1. Item 524980-25ML is packaged in a HDPE plastic bottle and 524980-100ML is packaged in an amber glass bottle.

      Helpful?

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