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Merck

287059

Sigma-Aldrich

L-脯氨酰胺

98%, for peptide synthesis

别名:

(2S)-2-Carbamoylpyrrolidine

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About This Item

经验公式(希尔记法):
C5H10N2O
CAS号:
分子量:
114.15
Beilstein:
80807
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.22

产品名称

L-脯氨酰胺, 98%

质量水平

方案

98%

旋光性

[α]20/D −106°, c = 1 in ethanol

反应适用性

reaction type: solution phase peptide synthesis

mp

95-97 °C (lit.)

应用

peptide synthesis

SMILES字符串

NC(=O)[C@@H]1CCCN1

InChI

1S/C5H10N2O/c6-5(8)4-2-1-3-7-4/h4,7H,1-3H2,(H2,6,8)/t4-/m0/s1

InChI key

VLJNHYLEOZPXFW-BYPYZUCNSA-N

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jinsuo Gao et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 16(26), 7852-7858 (2010-05-29)
Chirally functionalized hollow nanospheres with different surface properties were successfully synthesized by co-condensation of (2S,1'R,2'R)-N-tert-butyloxycarbonylpyrrolidine-2-carboxylic acid [2'-(4-trimethoxysilylbenzylamide)cyclohexyl] amide with 1,2-bis(trimethoxysilyl)ethane or tetramethoxysilane using F127 (EO(106)PO(70)EO(106)) as surfactant in water. The TEM and N(2) sorption characterizations show that the particle size
Stamatis Fotaras et al.
Organic & biomolecular chemistry, 10(29), 5613-5619 (2012-06-22)
A tripeptide-like prolinamide-thiourea catalyst with (S)-proline, (1S,2S)-diphenylethylenediamine and (S)-di-tert-butyl aspartate as building blocks provides the products of the reaction between ketones and aromatic aldehydes in high to quantitative yields and high stereoselectivities (up to 99:1 dr and 99% ee). Both
Rajasekhar Dodda et al.
Organic letters, 8(21), 4911-4914 (2006-10-06)
[reaction: see text] The first organocatalytic cross aldol reaction of ketones and diethyl formylphosphonate hydrate has been realized by using readily available l-prolinamide as the catalyst. Secondary alpha-hydroxyphosphonates have been synthesized in high enantioselective (up to >99% ee) and good
Jia-Rong Chen et al.
Organic letters, 7(20), 4543-4545 (2005-09-24)
[reaction: see text] Readily tunable and bifunctional L-prolinamides as novel organocatalysts have been developed, and their catalytic activities were evaluated in the direct asymmetric Aldol reactions of various aromatic aldehydes and cyclohexanone. High isolated yields (up to 94%), enantioselectivities (up
Sampak Samanta et al.
Organic letters, 7(23), 5321-5323 (2005-11-05)
[reaction: see text] The catalytic activity of the prolinamide-type catalysts may be improved by introducing additional prolinamide moiety into the catalyst, while the enantioselectivity can still be maintained or further improved. A C2-symmetric bisprolinamide with two prolinamide moieties has been

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