214965

氢化二异丁基铝 溶液

1.0 M in heptane

• 别名: DIBAL, DIBAL-H
• 线性分子式: [(CH₃)₂CHCH₂]₂AlH
• CAS号: 1191-15-7
• 分子量: 142.22
• Beilstein: 4123663
• MDL號碼: MFCD00008928
• 分類程式碼代碼: 12352001
• PubChem物質ID: 24852857
• NACRES: NA.22

属性

• 形狀: liquid
• 品質等級: 200
• 反應適用性: reagent type: reductant
• 濃度: 1.0 M in heptane
• 密度: 0.731 g/mL at 25 °C
• SMILES 字串: CC(C)C[AlH]CC(C)C
• InChI: 1S/2C4H9.Al.H/c2*1-4(2)3;;/h2*4H,1H2,2-3H3;;
• InChI 密鑰: AZWXAPCAJCYGIA-UHFFFAOYSA-N

说明

應用

Diisobutylaluminum hydride (DIBAL-H) is a common reducing agent to reduce aldehydes, ketones, esters, acids and acid chlorides to the corresponding alcohols. Some of the applications are:

• Synthesis of α-acetoxy ethers by reduction and subsequent acetylation of esters.
• Synthesis of coniferyl, sinapyl, and p-coumaryl alcohol by selective reduction of corresponding cinnamate esters.
• Reduction of secondary phosphine oxides (SPOs) to the corresponding phosphines.
• DIBAL-H can also be used in the hydroalumination of alkene and alkynes.

用于Pd催化的仲烷基溴的还原脱溴过程。过苄基化呋喃糖苷的O-脱苄基和开环。方便从 ZrCp₂Cl₂ 和DIBAL-H原位生成 HZrCp₂Cl。

安全信息

• 象形圖: GHS02,GHS08,GHS05,GHS07,GHS09
• 訊號詞: Danger
• 危險聲明: H225,H250,H260,H304,H314,H336,H410
• 防範說明: P210 - P231 + P232 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P370 + P378
• 危險分類: Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Skin Corr. 1B - STOT SE 3 - Water-react 1
• 標靶器官: Central nervous system
• 安全危害: EUH014
• 儲存類別代碼: 4.2 - Pyrophoric and self-heating hazardous materials
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 30.2 °F
• 閃點（°C）: -1 °C