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化驗
98%
形狀
solid
mp
81-83 °C (lit.)
SMILES 字串
Nc1ccc(Cl)nc1
InChI
1S/C5H5ClN2/c6-5-2-1-4(7)3-8-5/h1-3H,7H2
InChI 密鑰
QAJYCQZQLVENRZ-UHFFFAOYSA-N
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一般說明
5-氨基-2-氯吡啶可与空间受阻的2,6-二甲基苯基硼酸进行Suzuki-Miyaura偶联。它可通过Sandmeyer反应利用溴化物对氯化物进行易受温度影响的置换反应而生成2,5-二溴吡啶。
應用
5-氨基-2-氯吡啶已被用于合成[2H5]2-氨基-l-甲基-6-苯基咪唑[4,5-b]吡啶。它已被用于鉴定和评估分子印迹聚合物，用于从药物中选择性去除潜在的遗传毒性氨基吡啶杂质。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Unexpected Displacements of Chloride by Bromide Found During Sandmeyer Reactions of 3-or 5-Amino-2-chloropyridines.
Krapcho AP and Haydar SN.
Heterocyclic Communications, 4(4), 291-292 (1998)
A M Lynch et al.
Cancer research, 52(22), 6216-6223 (1992-11-15)
During the cooking of beef, the genotoxic heterocyclic aromatic amines 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline (DiMeIQx), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) are formed. Little is known about the fate of these compounds in humans or the factors affecting it. We have developed assays based
A highly active catalyst for Suzuki-Miyaura cross-coupling reactions of heteroaryl compounds.
Kelvin L Billingsley et al.
Angewandte Chemie (International ed. in English), 45(21), 3484-3488 (2006-04-28)
Fast identification of selective resins for removal of genotoxic aminopyridine impurities via screening of molecularly imprinted polymer libraries.
Kecili R, et al. et al.
Journal of Chromatography A (2014)
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