推荐产品
方案
99%
表单
solid
mp
39-41 °C (lit.)
官能团
bromo
SMILES字符串
BrCc1cccc(Br)c1
InChI
1S/C7H6Br2/c8-5-6-2-1-3-7(9)4-6/h1-4H,5H2
InChI key
ZPCJPJQUVRIILS-UHFFFAOYSA-N
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一般描述
3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.
应用
3-Bromobenzyl bromide was used in the synthesis of:
- 1,7-di(3-bromobenzyl)cyclen
- substituted 8-arylquinoline, phosphodiesterase 4 (PDE4) inhibitors
警示用语：
Danger
危险声明
危险分类
Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 3
闪点(°F)
235.4 °F - closed cup
闪点(°C)
113 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
其他客户在看
Synthesis of a new family of bi-and polycyclic compounds via Pd-catalyzed amination of 1, 7-di (3-bromobenzyl) cyclen.
Averin AD, et al.
Tetrahedron Letters, 49(24), 3950-3954 (2008)
Reduction of benzylic halides with diethylzinc using tetrakis (triphenylphosphine) palladium as catalyst.
Agrios KA and Srebnik M.
The Journal of Organic Chemistry, 58(24), 6908-6910 (1993)
Dwight Macdonald et al.
Bioorganic & medicinal chemistry letters, 15(23), 5241-5246 (2005-09-20)
The discovery and SAR of a new series of substituted 8-arylquinoline PDE4 inhibitors are herein described. This work has led to the identification of several compounds with excellent in vitro and in vivo profiles, including a good therapeutic window of
William L Scott et al.
Journal of combinatorial chemistry, 11(1), 14-33 (2008-12-25)
Distributed Drug Discovery (D(3)) proposes solving large drug discovery problems by breaking them into smaller units for processing at multiple sites. A key component of the synthetic and computational stages of D(3) is the global rehearsal of prospective reagents and
William L Scott et al.
Journal of combinatorial chemistry, 11(1), 34-43 (2008-12-25)
For the successful implementation of Distributed Drug Discovery (D(3)) (outlined in the accompanying Perspective), students, in the course of their educational laboratories, must be able to reproducibly make new, high quality, molecules with potential for biological activity. This article reports
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