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品質等級
化驗
99%
形狀
solid
mp
70-73 °C (lit.)
溶解度
chloroform: soluble 50 mg/mL, clear to very slightly hazy, faintly yellow
SMILES 字串
[O-][N+](=O)c1ccc(CCl)cc1
InChI
1S/C7H6ClNO2/c8-5-6-1-3-7(4-2-6)9(10)11/h1-4H,5H2
InChI 密鑰
KGCNHWXDPDPSBV-UHFFFAOYSA-N
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一般說明
用对硝基苯氯作为谷胱甘肽 S-转移酶 (GST) 的底物测定中国人胎肝中的 GST 。它被 NADPH 还原生成 4-硝基甲苯 。
應用
用对硝基氯化苄不对称合成了 N，N′- 双 （取代）4,13-二氮杂-18-冠-6-醚衍生物。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 4 Oral - Skin Corr. 1B
儲存類別代碼
8A - Combustible corrosive hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
其他客户在看
S B Lei et al.
Zhongguo yao li xue bao = Acta pharmacologica Sinica, 11(5), 389-391 (1990-09-01)
Subcellular fractions were isolated from Chinese fetal liver at 4-8 months of age for the determination of glutathione S-transferase (GST). Using 1-chloro-2,4-dinitrobenzene (CDNB) as substrate, GST activity was found to be 66 +/- 34 nmol/(min.mg protein), mainly in the cytosol.
D Mansuy et al.
Biochemical pharmacology, 32(12), 1871-1879 (1983-06-15)
The benzyl halides benzyl bromide and 4-nitrobenzyl chloride are reduced anaerobically by NADPH and rat liver microsomes to yield toluene and 4-nitrotoluene, respectively. These reductions and cytochrome P-450-dependent since they are inhibited by CO and metyrapone, and are increased after
J J Jaffe et al.
Molecular and biochemical parasitology, 20(2), 199-206 (1986-08-01)
Glutathione S-transferase (EC 2.5.1.18) was detected in the cytosolic and microsomal fractions of adult Dirofilaria immitis females at respective levels of 30 nmol and 3 nmol min-1 (mg protein)-1 activity with the substrate 1-chloro-2,4-dinitrobenzene (CDNB). The transferase activity in the
S V Singh et al.
Experimental eye research, 41(3), 405-413 (1985-09-01)
When rats were orally administered a daily dose of 300 mg kg-1 body weight of 3,5-di-t-butyl-4-hydroxytoluene (BHT) for 4 days, about 90% increase over basal level in total glutathione (GSH) S-transferase activity towards 1-chloro-2,4-dinitrobenzene (CDNB) was observed in ocular lens.
Kristine L Richardson et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 150(2), 279-284 (2009-05-23)
Glutathione s-transferases (GST) play a critical role in the detoxification of exogenous and endogenous electrophiles, as well as the products of oxidative stress. As compared to mammals, GST activity has not been extensively characterized in reptiles. Throughout the globe, most
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