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Merck

133973

Sigma-Aldrich

溴乙酸乙酯

reagent grade, 98%

别名:

Bromoacetic acid ethyl ester, Ethyl 2-bromoacetate

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About This Item

线性分子式:
BrCH2COOC2H5
CAS号:
分子量:
167.00
Beilstein:
506456
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

等級

reagent grade

蒸汽壓力

2.6 mmHg ( 25 °C)

化驗

98%

形狀

liquid

折射率

n20/D 1.451 (lit.)

bp

159 °C (lit.)

溶解度

water: insoluble

密度

1.506 g/mL at 25 °C (lit.)

SMILES 字串

CCOC(=O)CBr

InChI

1S/C4H7BrO2/c1-2-7-4(6)3-5/h2-3H2,1H3

InChI 密鑰

PQJJJMRNHATNKG-UHFFFAOYSA-N

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一般說明

溴代乙酸乙酯常在有机合成中用作为烷化剂和酰化试剂。溴代乙酸乙酯与叔丁基杯[4]芳烃进行衍生化反应,生成1,3-二酯取代的杯[4]芳烃。它还与芳基硼酸在氧化铜(I)共催化下发生Suzuki型交叉偶联反应

應用

溴乙酸乙酯用于在水性介质中制备可逆光敏香豆素稳定的聚合物纳米颗粒,其可用作可检测的药物载体

象形圖

FlameSkull and crossbones

訊號詞

Danger

危險分類

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Flam. Liq. 3

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

116.6 °F - closed cup

閃點(°C)

47 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Jae Woo Chung et al.
Small (Weinheim an der Bergstrasse, Germany), 8(11), 1693-1700 (2012-03-29)
The ability to create aqueous suspended stable nanoparticles of the hydrophobic homopolymer poly(ϵ-caprolactone) end-functionalized with coumarin moieties (CPCL) is demonstrated. Nanoparticles of CPCL are prepared in a continuous manner using nanoprecipitation. The resulting nanoparticles are spherical in morphology, about 40
Synthesis and cytotoxicity of 28-carboxymethoxy lupane triterpenoids. Preference of 28-O-acylation over 28-O-alkylation of betulin by ethyl bromoacetate
AA Mar, et al.
Chinese Chemical Letters = Zhongguo Hua Xue Kuai Bao, 20, 1141-1144 (2009)
Unusual pathway of alkylation of 2-(4-bromobenzylidene)-p-menthan-3-one with ethyl bromoacetate
AI Krivoshei, et al.
Russian Chemical Bulletin, 56, 2506-2509 (2007)
Gillian McMahon et al.
Talanta, 57(6), 1119-1132 (2008-10-31)
A series of derivatisation reactions between p-t-butyl calix[4]arene and ethyl bromoacetate were carried out in order to prepare 1,3 diester substituted calix[4]arene. Mass spectral data, obtained from direct injection of samples, indicated that the reactions were rich in the desired
Sandu Cibotaru et al.
Materials science & engineering. C, Materials for biological applications, 116, 111216-111216 (2020-08-19)
The paper reports a series of three new PEGylated phenothiazine derivatives which keep the potential of valuable building blocks for preparing eco-materials addressed to a large realm of fields, from bio-medicine to opto-electronics. They were synthetized by connecting the hydrophilic

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