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149209

Sigma-Aldrich

Methyl methoxyacetate

99%

Synonym(s):

Methoxyacetic acid methyl ester, Methyl α-methoxyacetate, Methyl 2-methoxyacetate

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About This Item

Linear Formula:
CH3OCH2COOCH3
CAS Number:
Molecular Weight:
104.10
Beilstein:
1742944
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

form

liquid

refractive index

n20/D 1.396 (lit.)

bp

129-130 °C (lit.)

density

1.051 g/mL at 25 °C (lit.)

functional group

ester
ether

SMILES string

COCC(=O)OC

InChI

1S/C4H8O3/c1-6-3-4(5)7-2/h3H2,1-2H3

InChI key

QRMHDGWGLNLHMN-UHFFFAOYSA-N

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Application

Methyl methoxyacetate was used in the preparation of 4-hydroxy-2-mercapto-5-methoxypyrimidine (II).

Pictograms

Flame

Signal Word

Warning

Hazard Statements

Hazard Classifications

Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

Flash Point(F)

95.0 °F - closed cup

Flash Point(C)

35 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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888. Pyrimidines. Part XI. Synthesis of 5-hydroxypyrimidine and related compounds.
Chesterfield JH, et al.
Journal of the Chemical Society, 4590-4596 (1960)
Shigehiro Namiki et al.
The International journal of neuroscience, 119(2), 214-226 (2009-01-07)
Loading neurons with membrane permeable Ca2+ indicators is a core experimental procedure in functional multineuron Ca2+ imaging (fMCI), an optical technique for monitoring multiple neuronal activities. Although fMCI has been applied to several brain networks, including cerebral cortex, hippocampus, and
[Information from the Soviet Toxicology Center].
Farmakologiia i toksikologiia, 43(6), 750-751 (1980-11-01)
K Thompson et al.
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 87(7), 468-483 (2012-09-19)
Stimulated by difficulties experienced when using fluo-3 AM, we developed a general mechanistic model to aid understanding and practical application of calcium probes applied as acetoxymethyl (AM) esters. Several practical issues previously overlooked or under-emphasized are considered by this model.

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