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Z-004

Supelco

Zaleplon solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C17H15N5O
CAS Number:
151319-34-5
Molecular Weight:
305.33
EC Number:
200-659-6
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

CCN(C(C)=O)c1cccc(c1)-c2ccnc3c(cnn23)C#N

InChI

1S/C17H15N5O/c1-3-21(12(2)23)15-6-4-5-13(9-15)16-7-8-19-17-14(10-18)11-20-22(16)17/h4-9,11H,3H2,1-2H3

InChI key

HUNXMJYCHXQEGX-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554) , GABRB1(2560) , GABRG2(2566)

Related Categories

General description

Zaleplon is a nonbenzodiazepine “Z-drug” prescribed under the trade names Sonata® or Starnoc for the treatment of insomnia. Zaleplon is often abused illicitly for its mind-altering effects. This Certified Spiking Solution® is applicable to use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, and forensic analysis.

Application


  • Controlled pore glass beads: Controlled pore glass can be employed for sustainable functionalized metal-organic frameworks for CO2 separation, showcasing the material′s effectiveness in environmental applications due to its high BET surface area which enhances gas adsorption properties (Babar et al., 2021).

  • Porous glass for protein adsorption: Mesoporous nano-bioglass for controlled drug release, highlights the application of controlled pore glass with high surface areas in pharmaceutical formulations to enhance the delivery and efficacy of therapeutic agents (Shoaib et al., 2017).

  • Surface characterization materials: It can be employed for the contact angle hysteresis of materials with controlled pore structures, to understand the wetting properties of high surface area materials like controlled pore glass, which is critical in various industrial and biomedical applications (Salmas and Androutsopoulos, 2001).


Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Sonata is a registered trademark of King Pharmaceuticals Research and Development, Inc.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Charles B Schaffer et al.
Journal of affective disorders, 128(3), 305-308 (2010-08-13)
Insomnia in patients with bipolar disorder (BD) can cause distress, daytime dysfunction, cognitive impairment, worsening of hypomanic/manic symptoms and increased suicide risk. Physicians often prescribe hypnotics for BD patients with insomnia although no hypnotic has a specific FDA indication for
Monique A J Mets et al.
Sleep medicine reviews, 14(4), 259-267 (2010-02-23)
Disturbed body balance and standing steadiness are problematic for those who wake up at night or in the morning after using hypnotic drugs. As a result, falls and hip fractures are frequently reported in patients using sleep medication. A literature
Jasna Jablan et al.
Journal of pharmaceutical and biomedical analysis, 71, 35-44 (2012-08-18)
The aim of this work was to investigate the potential synergistic effect of water-soluble polymers (hypromellose, HPMC and polyvinylpyrrolidone, PVP) on zaleplon (ZAL) complexation with parent β-cyclodextrin (βCD) and its randomly methylated derivative (RAMEB) in solution and in solid state.
Adam R Lancaster et al.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 21(6), 658-665 (2012-02-10)
To summarize the signalment, clinical signs observed, time to onset of clinical signs, duration of clinical signs, and the outcome in a large case series of nonbenzodiazepine sleep aid ingestions in dogs, including 2 sleep aids that have not been
Yu-Shu Huang et al.
Chang Gung medical journal, 34(1), 50-56 (2011-03-12)
Benzodiazepines cause a high proportion of adverse effects while non-benzodiazepine compounds have demonstrated high efficacy and less adverse effects in patients with insomnia. The objective of this study was to compare the effectiveness and safety of non-BZ zaleplon and zolpidem
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