M217

Monoclonal Anti-Nicotinic Acetylcholine Receptor (α₁, α₃, α₅ Subunits) antibody produced in rat

clone mAb 35, purified immunoglobulin, buffered aqueous solution

• Synonyme(s) : Anti-ACHR
• Numéro MDL: MFCD00677279
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.43

Propriétés

• Source biologique: rat
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: mAb 35, monoclonal
• Forme: buffered aqueous solution
• Espèces réactives: human, chicken, eel
• Ne doit pas réagir avec: Xenopus
• Technique(s): immunohistochemistry (frozen sections): 1:3,000
• Isotype: IgG1
• Numéro d'accès UniProt: CHRNA1
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... CHRNA1(1134) , CHRNA3(1136) , CHRNA5(1138)

Description

Spécificité

Binds to the main immunogenic region on the extracellular surface of the α₁ subunit of muscle AChR′s and to homologous regions on α₃ and α₅ subunits of neuronal AChR′s. The epitope is located on the extracellular surface of the α₁ subunit of the muscle nicotinic acetylcholine receptor. The antibody binds to denatured chick α₅ AChR, but does not bind well to denatured α₃, α₄, α₇, α_8, and β₂. It may also bind β₃ due to homology of main immunogenic region. May be used to localize and detect the α₁, α₃ and α₅ subunits of the nicotinic acetylcholine receptor (AChR).

Immunogène

nicotinic acetylcholine receptor from the electric eel Electrophorus.

Forme physique

Solution in 20 mM Na₃PO₄, pH 7.2, containing 150 mM NaCl and 0.05 % sodium azide.

Informations légales

Sold with permission of the Salk Institute

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)