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80666

Sigma-Aldrich

Hexarelin

≥90% (HPLC)

Synonyme(s) :

HEX, L-Histidyl-2-methyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide, Examorelin

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About This Item

Formule empirique (notation de Hill):
C47H58N12O6
Numéro CAS:
140703-51-1
Poids moléculaire :
887.04
Code UNSPSC :
12352209
ID de substance PubChem :
329769022
Nomenclature NACRES :
NA.26

product name

Hexarelin, ≥90% (HPLC)

Niveau de qualité

100

Pureté

≥90% (HPLC)

Forme

powder

Couleur

white

Solubilité

H2O: 1 mg/mL, clear, colorless

Température de stockage

−20°C

Chaîne SMILES 

C[C@H](NC(=O)[C@@H](Cc1c(C)[nH]c2ccccc12)NC(=O)[C@@H](N)Cc3cnc[nH]3)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@H](Cc6ccccc6)C(=O)N[C@@H](CCCCN)C(N)=O

InChI

1S/C47H58N12O6/c1-27-34(33-15-7-9-17-37(33)54-27)23-41(58-44(62)35(49)22-31-25-51-26-53-31)45(63)55-28(2)43(61)57-40(21-30-24-52-36-16-8-6-14-32(30)36)47(65)59-39(20-29-12-4-3-5-13-29)46(64)56-38(42(50)60)18-10-11-19-48/h3-9,12-17,24-26,28,35,38-41,52,54H,10-11,18-23,48-49H2,1-2H3,(H2,50,60)(H,51,53)(H,55,63)(H,56,64)(H,57,61)(H,58,62)(H,59,65)/t28-,35-,38-,39+,40-,41+/m0/s1

Clé InChI

RVWNMGKSNGWLOL-GIIHNPQRSA-N

Catégories apparentées

Actions biochimiques/physiologiques

Hexarelin (HEX), a ghrelin analogue, is a growth hormone secretagogue receptor agonist, a growth hormone releasing peptide. Hexarelin may be used as an internal standard in quantitative analysis (via chromatography etc.) of prohibited growth hormone enhancing drugs such as GHRP-2. The potential use of Hexarelin as a therapeutic has prompted research studies on its physiological effects in vitro and in vivo.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Erin M Euliano et al.
Scientific reports, 9(1), 11372-11372 (2019-08-08)
Reverse transcription polymerase chain reaction (RT-PCR) is the gold standard for the molecular diagnosis of many infectious diseases, including RNA viruses, but is generally limited to settings with access to trained personnel and laboratory resources. We have previously reported a
Luca Cavallone et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 28(5), 909-916 (2019-03-03)
Circulating free DNA (cfDNA) is an exciting novel method to diagnose, monitor, and predict resistance and response to cancer therapies, with the potential to radically alter the management of cancer patients. To fulfill its potential, greater knowledge about preanalytical variables
Junshi Matsuda et al.
PloS one, 12(3), e0173489-e0173489 (2017-03-17)
The Amami Island group of the Ryukyu Archipelago, Japan, harbors extensive species diversity of Asarum in a small landmass. The fine-scale population genetic structure and diversity of nine insular endemic Asarum species were examined using nuclear DNA microsatellite loci and
Georges Khoury et al.
Nucleic acids research, 48(5), 2643-2660 (2019-12-26)
Tat protein is essential to fully activate HIV transcription and processing of viral mRNA, and therefore determines virus expression in productive replication and the establishment and maintenance of latent infection. Here, we used thermodynamic and structure analyses to define a
Olivier Humbert et al.
Science translational medicine, 11(503) (2019-08-02)
Reactivation of fetal hemoglobin (HbF) is being pursued as a treatment strategy for hemoglobinopathies. Here, we evaluated the therapeutic potential of hematopoietic stem and progenitor cells (HSPCs) edited with the CRISPR-Cas9 nuclease platform to recapitulate naturally occurring mutations identified in
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