PHR1026

Ranitidine hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyme(s) : N, N Dimethyl-5-[2-(1-methylamine-2-nitrovinyl)-ethylthiomethyl]furfurylamine hydrochloride
• Formule empirique (notation de Hill): C₁₃H₂₂N₄O₃S · HCl
• Numéro CAS: 66357-59-3
• Poids moléculaire : 350.86
• Numéro CE : 266-333-0
• Numéro MDL: MFCD00069339
• Code UNSPSC : 41116107
• ID de substance PubChem : 329823056
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material; pharmaceutical secondary standard
• Niveau de qualité: 300
• Agence: traceable to BP 471; traceable to Ph. Eur. R0150000; traceable to USP 1598405
• Famille d'API: ranitidine
• CofA (certificat d'analyse): current certificate can be downloaded
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-30°C
• Chaîne SMILES: Cl[H].CN\C(NCCSCc1ccc(CN(C)C)o1)=C\[N+]([O-])=O
• InChI: 1S/C13H22N4O3S.ClH/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3;/h4-5,9,14-15H,6-8,10H2,1-3H3;1H/b13-9-;
• Clé InChI: GGWBHVILAJZWKJ-CHHCPSLASA-N

Description

Description générale

Ranitidine hydrochloride is a H₂-receptor antagonist, widely used for the management of hypersecretory conditions and for the treatment of duodenal ulcer.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Ranitidine hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using titrimetry and visible spectrophotometry techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Actions biochimiques/physiologiques

H2 histamine receptor antagonist; anti-ulcer agent.

H₂ histamine receptor antagonist; anti-ulcer agent.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAA5630 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informations sur la sécurité

• Pictogrammes: GHS08,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H315,H317,H319,H334,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable