901767

PC biotin-PEG3-NHS ester

• Synonyme(s) : PC biotin-NHS ester
• Formule empirique (notation de Hill): C₃₆H₅₂N₆O₁₅S
• Numéro CAS: 2353409-93-3
• Poids moléculaire : 840.89
• Code UNSPSC : 51171641
• Nomenclature NACRES : NA.22

Propriétés

• Forme: solid
• Capacité de réaction: reaction type: click chemistry
• Pertinence de la réaction: reagent type: cross-linking reagent
• Pf: 170 °C
• Température de stockage: −20°C

Description

Application

PC biotin-NHS ester is a unique amine-reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm²).

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Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable