114529

Phenol Red

ACS reagent

• Synonyme(s) : Phenolsulfonphthalein
• Formule empirique (notation de Hill): C₁₉H₁₄O₅S
• Numéro CAS: 143-74-8
• Poids moléculaire : 354.38
• Numéro Beilstein : 326470
• Numéro CE : 205-609-7
• Numéro MDL: MFCD00003552
• Code UNSPSC : 12171500
• ID de substance PubChem : 24847179
• Nomenclature NACRES : NA.47

Propriétés

• Qualité: ACS reagent
• Niveau de qualité: 200
• Forme: powder
• Limpidité de la solution: passes test
• Technique(s): titration: suitable
• visual transition interval: 6.8-8.2, yellow to red
• Solubilité: water: 0.77 g/L at 100 °C
• λmax: 360 nm; 557 nm (2nd)
• ε (coefficient d'extinction): ≥10000 at 288-294 nm in H₂O; ≥55000 at 555-561 nm in H₂O; ≥7000 at 357-363 nm in H₂O
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: Oc1ccc(cc1)C2(OS(=O)(=O)c3ccccc23)c4ccc(O)cc4
• InChI: 1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H
• Clé InChI: BELBBZDIHDAJOR-UHFFFAOYSA-N

Description

Description générale

Phenol Red is a phenolsulfonphthalein compound. It is present as a sulfonated hydroxyquinone in weakly acidic aqueous solutions. In alkaline solutions, the dye forms a hydrophilic dianion (a small, red anion that has a larger conjugated system than the yellow hydroxyquinone).

Application

Phenol red is commonly used as a pH indicator in biology and medicine. It is incorporated into microbiological culture media for the identification of Escherichia coli strains. Its clinical diagnostic applications include the investigation of gastric and duodenal ulcers and the assessment of tear function in ophthalmology. Phenol red is also used as a tracer to assess the permeability of the ileal mucosal membrane and to assess bacterial leakage through root-filling materials in dentistry.
Phenol Red has been used for the preparation of phenol red gavage meal for measurement of gastric emptying in rats.

Suitable for use as a pH indicator.

Actions biochimiques/physiologiques

Phenol Red is a pH indicator which changes color from yellow to red.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P304 + P340 + P312
• Classification des risques: Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves