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Principaux documents

MAB1978

Sigma-Aldrich

Anti-Integrin αV Antibody, clone LM142

ascites fluid, clone LM142, Chemicon®

Synonyme(s) :

CD51

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

ascites fluid

Type de produit anticorps

primary antibodies

Clone

LM142, monoclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable

Isotype

IgG1

Adéquation

not suitable for activity/function inhibition

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ITGAV(3685)

Spécificité

Reactive with integrin alpha-V.

Application

Detect Integrin αV using this Anti-Integrin αV Antibody, clone LM142 validated for use in IP, IH.
Immunohistochemistry (Acetone Fixed Only) 1:1000

Immunofluorescence and immunoprecipitation.

MAB1978 is non-blocking.

Final working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Stockage et stabilité

Maintain at -20°C for up to 12 months. Avoid repeated freeze/thaw cycles.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Masako Ueda et al.
Biomaterials, 31(25), 6394-6399 (2010-06-12)
We previously showed that blood outgrowth endothelial cells (BOECs) had a high affinity for polyurethane (PU) covalently configured with cholesterol residues (PU-Chol). However, the molecular mechanisms responsible for this enhanced affinity were not determined. CD47, a multifunctional transmembrane glycoprotein involved
M O De Nichilo et al.
The Journal of biological chemistry, 271(18), 11016-11022 (1996-05-03)
The macrophage colony-stimulating factor (M-CSF) is able to induce the expression of the alpha v beta 5 integrin receptor on the surface of cultured human macrophages (De Nichilo, M. O., and Burns, G. F. (1993) Proc. Natl. Acad. Sci. U.S.A.
Robert McMillan et al.
British journal of haematology, 118(4), 1132-1136 (2002-08-30)
In chronic immune thrombocytopenic purpura (ITP), autoantibodies bind to platelet surface proteins, particularly alphaIIb, resulting in platelet destruction by the reticulo-endothelial system. In order to better localize the autoepitopes on alphaIIb, we studied the binding of antibodies to Chinese hamster
Tatiana Gianni et al.
PLoS pathogens, 9(12), e1003806-e1003806 (2013-12-25)
Herpes simplex virus (HSV)--and herpesviruses in general--encode for a multipartite entry/fusion apparatus. In HSV it consists of the HSV-specific glycoprotein D (gD), and three additional glycoproteins, gH/gL and gB, conserved across the Herpesviridae family and responsible for the execution of
Jing Huang et al.
Blood, 113(7), 1589-1597 (2008-10-18)
Acutely secreted von Willebrand factor (VWF) multimers adhere to endothelial cells, support platelet adhesion, and may induce microvascular thrombosis. Immunofluorescence microscopy of live human umbilical vein endothelial cells showed that VWF multimers rapidly formed strings several hundred micrometers long on

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