324744-M

Elastase Inhibitor II

The Elastase Inhibitor II controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• Synonyme(s) : Elastase Inhibitor II, HNE Inhibitor, MeOSuc-AAPA-CMK, MSACK
• Formule empirique (notation de Hill): C₂₀H₃₁ClN₄O₇
• Poids moléculaire : 474.94
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥99% (TLC)
• Forme: lyophilized solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated
• Couleur: white
• Solubilité: DMSO: 10 mg/mL; methanol: soluble
• Température de stockage: −20°C

Description

Description générale

A potent inhibitor of human neutrophil elastase (HNE).The inhibition results from cross-linking of catalytic residues His⁵⁷ and Ser¹⁹⁵ in the HNE in the presence of this inhibitor.

A potent irreversible inhibitor of human neutrophil elastase (HNE). Inhibition results from cross-linking of the catalytic residues His⁵⁷ and Ser¹⁹⁵.

Actions biochimiques/physiologiques

Primary Target
Human neutrophil elastase (HNE)

Avertissement

Toxicity: Standard Handling (A)

Séquence

MeOSuc-Ala-Ala-Pro-Ala-CMK

Reconstitution

Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.

Autres remarques

Navia, M.A., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7.
Williams, H.R., et al. 1987. J. Biol. Chem.262, 17178.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable