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PHR1529

Supelco

Menthyl anthranilate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Menthyl anthranilate, Menthyl o-aminobenzoate

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About This Item

Empirical Formula (Hill Notation):
C17H25NO2
CAS Number:
Molecular Weight:
275.39
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1381742

API family

meradimate

CofA

current certificate can be downloaded

packaging

ampule of 1 × 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.542 (lit.)

bp

177-179 °C/3 mmHg (lit.)

density

1.04 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)C1CCC(C)CC1OC(=O)c2ccccc2N

InChI

1S/C17H25NO2/c1-11(2)13-9-8-12(3)10-16(13)20-17(19)14-6-4-5-7-15(14)18/h4-7,11-13,16H,8-10,18H2,1-3H3

InChI key

SOXAGEOHPCXXIO-UHFFFAOYSA-N

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General description

Menthyl anthranilate, popularly known as meradimate, is a broad-spectrum UV sunscreen agent. It is commonly used in personal care products including sunscreens, hair care, and cosmetic products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Menthyl anthranilate may be used as a pharmaceutical reference standard for the determination of the analyte in raw materials and personal care products by high performance liquid chromatography and gas chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA3647 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Pictograms

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Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Determination of sunscreen compounds in topical sunscreen products
DiNunzio JE and Gadde RR
Journal of Chromatography A, 519(1), 117-124 (1990)
Photophysics of the sunscreen ingredient menthyl anthranilate and its precursor methyl anthranilate: A bottom-up approach to photoprotection
Rodrigues NDN, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 353(1), 376-384 (2018)
Simultaneous analysis and monitoring of 16 UV filters in cosmetics by high-performance liquid chromatography.
Kim D, et al.
Journal of Cosmetic Science, 63(2), 103-117 (2012)
Optimization of an analytical methodology for the simultaneous determination of different classes of ultraviolet filters in cosmetics by pressurized liquid extraction-gas chromatography tandem mass spectrometry
Vila M, et al.
Journal of Chromatography A, 1405(1), 12-22 (2015)
Wavepacket insights into the photoprotection mechanism of the UV filter methyl anthranilate
Rodrigues NDN, et al.
Nature Communications, 9(1), 5188-5188 (2018)

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