PHR1046
Ethylene glycol
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
Monoethylene glycol, 1,2-Ethanediol
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About This Item
Linear Formula:
HOCH2CH2OH
CAS Number:
Molecular Weight:
62.07
Beilstein:
505945
EC Number:
MDL number:
UNSPSC Code:
41116107
eCl@ss:
39020501
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to USP 1265515
vapor density
2.1 (vs air)
vapor pressure
0.08 mmHg ( 20 °C)
CofA
current certificate can be downloaded
autoignition temp.
752 °F
expl. lim.
15.3 %
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
refractive index
n20/D 1.431 (lit.)
bp
195-198 °C
mp
−13 °C (lit.)
density
1.113 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
OCCO
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ethylene glycol can also be produced from fossil fuels (petroleum, natural gas and coal) and biomass-derived resources. It is a polyol having a wide range of industrial applications.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Ethylene glycol may be used as a standard in the determination of ethylene glycol present in serum samples using gas chromatography (GC).
Analysis Note
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAC2089 in the slot below. This is an example certificate only and may not be the lot that you receive.
Recommended products
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - STOT RE 2 Oral
Target Organs
Kidney
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
239.0 °F - open cup
Flash Point(C)
115 °C - open cup
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Gas-chromatographic determination of ethylene glycol in serum
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Journal of the American Chemical Society, 135(5), 1941-1951 (2013-01-16)
This article describes a robust method for the facile synthesis of small Ag nanocubes with edge lengths controlled in the range of 18-32 nm. The success of this new method relies on the substitution of ethylene glycol (EG)--the solvent most
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The electrooxidation of ethylene glycol (EG) and glycerol (G) has been studied: in alkaline media, in passive as well as active direct ethylene glycol fuel cells (DEGFCs), and in direct glycerol fuel cells (DGFCs) containing Pd-(Ni-Zn)/C as an anode electrocatalyst
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