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1708707

USP

Valproinsäure

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

2-Propylpentansäure, 2-Propylvaleriansäure

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About This Item

Lineare Formel:
(CH3CH2CH2)2CHCO2H
CAS-Nummer:
99-66-1
Molekulargewicht:
144.21
EG-Nummer:
202-777-3
MDL-Nummer:
MFCD00002672
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329751478
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

valproic acid

Hersteller/Markenname

USP

Brechungsindex

n20/D 1.425 (lit.)

bp

220 °C (lit.)

Dichte

0.9 g/mL at 25 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

SMILES String

CCCC(C(O)=O)CCC

InChI

1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)

InChIKey

NIJJYAXOARWZEE-UHFFFAOYSA-N

Angaben zum Gen

human ... ALDH5A1(7915)

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Valproic acid USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Divalproex Sodium
  • Divalproex Sodium Delayed-Release Capsules
  • Divalproex Sodium Delayed-Release Tablets
  • Divalproex Sodium Extended-Release Tablets
  • Valproate Sodium Injection
  • Valproic Acid
  • Valproic Acid Capsules

Biochem./physiol. Wirkung

Antikonvulsivum, das auch eine Wirkung als Stimmungsstabilisator bei einer bipolaren Störung besitzt.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1A - Skin Irrit. 2

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

231.8 °F - closed cup

Flammpunkt (°C)

111 °C - closed cup

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Sigma-Aldrich

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Sigma-Aldrich

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Taylor Chomiak et al.
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Inflammation and vascular perturbations are increasingly implicated in the pathogenesis of neurodegenerative diseases. Prevailing evidence suggests that valproic acid (VPA), an antiepileptic and mood stabilizer, exhibits not only neuro-protective effects, but also anti-inflammatory effects in neurodegenerative diseases. However, the underlying
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Liver injury is the leading cause of drug-induced toxicity. For the evaluation of a chemical compound to induce toxicity, in this case steatosis or fatty liver, it is imperative to identify markers reflective of mechanisms and processes induced upon exposure
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The mood stabilizers lithium and valproic acid (VPA) are traditionally used to treat bipolar disorder (BD), a severe mental illness arising from complex interactions between genes and environment that drive deficits in cellular plasticity and resiliency. The therapeutic potential of
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The novel SARS-CoV-2 virus emerged in December 2019 and has few effective treatments. We applied a computational drug repositioning pipeline to SARS-CoV-2 differential gene expression signatures derived from publicly available data. We utilized three independent published studies to acquire or
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