V4765

Valnoctamide

≥98% (NMR)

• Synonym(e): 2-ethyl-3-methyl-pentanamide, Axiquel, Nirvanil
• Empirische Formel (Hill-System): C₈H₁₇NO
• CAS-Nummer: 4171-13-5
• Molekulargewicht: 143.23
• MDL-Nummer: MFCD00868184
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329829054
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (NMR)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to off-white
• Löslichkeit: DMSO: 20 mg/mL, clear
• Lagertemp.: room temp
• SMILES String: CCC(C)C(CC)C(N)=O
• InChI: 1S/C8H17NO/c1-4-6(3)7(5-2)8(9)10/h6-7H,4-5H2,1-3H3,(H2,9,10)
• InChIKey: QRCJOCOSPZMDJY-UHFFFAOYSA-N

Beschreibung

Anwendung

Valnoctamide has been used:

• as a mood stabilizer to study its anti-cytomegalovirus (anti-CMV) effects in newborn mice brain
• as a hypnotic sedative to study its cytotoxic effects on oligodendrocyte precursor cells (OPCs) and human oligodendroglioma cell line (HOG)
• as a mood stabilizer to study its effects on inhibition of human cytomegalovirus

Biochem./physiol. Wirkung

Valnoctamide exhibits anti-cytomegalovirus (anti-CMV) properties. It has therapeutic effects against status epilepticus (SE) and neuropathic pain. Valnoctamide also shows therapeutic effects against bipolar disorders.

Valproic acid (VPA) and derivatives such as valpromide and valnoctamide are anti-convulsant, mood stabilizing drugs, believed to function as indirect GABA agonists by inhibiting the transamination of GABA.

Leistungsmerkmale und Vorteile

This compound is featured on the Glutamate/GABA Synthesis and Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable