1370462

Losartan-Kalium

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): 2-Butyl-4-chlor-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-Imidazol-5-methanol-Kaliumsalz, 2-Butyl-4-chlor-1-{[2′-(1H-tetrazol-5-yl)-(1,1′-biphenyl)-4-yl]-methyl}-1H-imidazol-5-methanol Monokaliumsalz, DuP 753, Kalium-5-(4′-((2-butyl-4-chlor-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)-[1,1′-biphenyl]-2-yl)tetrazol-1-id, MK 954
• Empirische Formel (Hill-System): C₂₂H₂₂ClKN₆O
• CAS-Nummer: 124750-99-8
• Molekulargewicht: 461.00
• Beilstein: 5845770
• MDL-Nummer: MFCD02092704
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329750264
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: losartan
• Hersteller/Markenname: USP
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• SMILES String: CCCCc1nc(Cl)c(CO)n1Cc2ccc(cc2)-c3ccccc3-c4nnnn4[K]
• InChI: 1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
• InChIKey: OXCMYAYHXIHQOA-UHFFFAOYSA-N
• Angaben zum Gen: human ... AGTR1(185)

Beschreibung

Allgemeine Beschreibung

Losartan potassium is a new drug used for hypertension. It is nonpeptide angiotensin II (AII) receptor antagonist.

Losartan potassium is nonpeptide angiotensin II (AII) receptor antagonist and is orally active. It belongs to a new class of drugs introduced for clinical trials to treat hypertension.

Anwendung

Losartan potassium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Losartan Potassium and Hydrochlorothiazide Tablets
• Losartan Potassium Tablets

Biochem./physiol. Wirkung

Losartankalium ist ein oral verabreichter, wirksamer und selektiver kompetitiver Angiotensin-II-Rezeptortyp-1(AT1)-Antagonist. Losartankalium wird zur Behandlung von Hypertonie eingesetzt.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable