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1361010

USP

Levadopa-verwandte Verbindung A

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

2,5-Dihydroxy-L-tyrosin, 3-(2,4,5-Trihydroxyphenyl)-L-alanin

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About This Item

Empirische Formel (Hill-System):
C9H11NO5
CAS-Nummer:
Molekulargewicht:
213.19
MDL-Nummer:
UNSPSC-Code:
41116107
NACRES:
NA.24

Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Qualität

pharmaceutical primary standard

API-Familie

levadopa

Hersteller/Markenname

USP

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

[N+H3][C@@H](Cc1c(cc(c(c1)O)O)O)C(=O)[O-]

InChI

1S/C9H11NO5/c10-5(9(14)15)1-4-2-7(12)8(13)3-6(4)11/h2-3,5,11-13H,1,10H2,(H,14,15)/t5-/m0/s1

InChIKey

YLKRUSPZOTYMAT-YFKPBYRVSA-N

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Dieser Artikel
142000613610091095517
Levodopa United States Pharmacopeia (USP) Reference Standard

1361009

Levodopa

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

format

neat

format

neat

format

neat

format

neat

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

API family

levadopa

API family

levodopa

API family

levodopa

API family

carbidopa

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

-

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Levadopa Related Compound A USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral - Skin Irrit. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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    J Plastino et al.
    FEBS letters, 371(3), 276-278 (1995-09-11)
    Limited proteolysis of recombinant Hansenula polymorpha yeast amino oxidase produces a 48 kDa fragment which corresponds to the C-terminal two-thirds of the protein. The fragment contains both TOPA (2,4,5-trihydroxyphenylalanine) and copper, as well as the histidine ligands implicated in copper
    Mass spectrometric studies of the primary sequence and structure of bovine liver and serum amine oxidase.
    G W Adams et al.
    Methods in enzymology, 258, 90-114 (1995-01-01)
    H Yamato et al.
    Neuroreport, 12(6), 1123-1126 (2001-05-08)
    We investigated the effect of fluoxetine, a selective serotonin reuptake inhibitor (SSRI), on L-DOPA-derived extracellular dopamine (DA) levels in the striatum of rats with nigrostriatal dopaminergic denervation using in vivo microdialysis. Treatment with fluoxetine (10 mg/kg, i.p.) induced a 41%
    G Künig et al.
    Journal of neural transmission. Supplementum, 43, 59-62 (1994-01-01)
    Neurotoxic substances are discussed to cause neurodegeneration by acting as excitotoxins on glutamate receptors. We investigated the properties of L-beta-oxalyl-amino-alanine (L-BOAA) and 3,4, 6-trihydroxyphenlyalanine (6-OH-Dopa) at the alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) glutamate receptor and that of L-BOAA and domoic acid at
    R M Kostrzewa et al.
    Amino acids, 19(1), 183-199 (2000-10-12)
    To determine if greater amounts of hydroxyl radical (*OH) are formed by dopamine (DA) denervation and treatment with L-dihydroxyphenylalanine (L-DOPA), the neostriatum was DA denervated (99% reduction in DA content) by 6-hydroxydopamine treatment (134microg icv, desipramine pretreatment) of neonatal rats.

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