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1019701

USP

Amilorid -hydrochlorid

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

Amilorid -hydrochlorid Dihydrat, N-Amidino-3,5-diamino-6-chlorpyrazincarboxamid -hydrochlorid Dihydrat

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About This Item

Empirische Formel (Hill-System):
C6H8ClN7O · HCl · 2H2O
CAS-Nummer:
17440-83-4
Molekulargewicht:
302.12
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

amiloride

Hersteller/Markenname

USP

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

InChI

1S/C6H8ClN7O.ClH.2H2O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;;;/h(H4,8,9,13)(H4,10,11,14,15);1H;2*1H2

InChIKey

LTKVFMLMEYCWMK-UHFFFAOYSA-N

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Allgemeine Beschreibung

Amiloride hydrochloride is a photosensitive yellow powder used as a mild diuretic drug.

Anwendung

Amiloride hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Amiloride Hydrochloride and Hydrochlorothiazide Tablets
  • Amiloride Hydrochloride Tablets

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Matthias Schoenberger et al.
Expert opinion on therapeutic patents, 23(10), 1383-1389 (2013-08-21)
Novel molecular platforms for epithelial sodium channel (ENaC) modulators are claimed in the following six patents: WO2012035158(A1); WO2009074575(A2); WO2011028740(A1); WO2009150137(A2); WO2011079087(A1); WO2008135557(A1). These ENaC inhibitors may be used in blocking transepithelial sodium and consequently water absorption across airway epithelia. This
Yusuke Ito et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 306(5), R315-R327 (2014-01-10)
Zebrafish Na(+)/H(+) exchanger 3b (zNHE3b) is highly expressed in the apical membrane of ionocytes where Na(+) is absorbed from ion-poor fresh water against a concentration gradient. Much in vivo data indicated that zNHE3b is involved in Na(+) absorption but not
Hong Wang et al.
Hypertension (Dallas, Tex. : 1979), 62(4), 738-745 (2013-08-21)
In Dahl salt-sensitive rats (Dahl SS), glomerular capillary pressure increases in response to high salt intake and this is accompanied by significant glomerular injury compared with spontaneously hypertensive rats with similar blood pressure. Glomerular capillary pressure is controlled mainly by
Mónica C F Ferraro et al.
Journal of pharmaceutical and biomedical analysis, 30(4), 1121-1131 (2002-11-01)
The use of multivariate spectrophotometric calibration for the simultaneous analysis of synthetic samples and commercial tablet preparations containing hydrochlorothiazide (HCT) and amiloride hydrochloride (AMH) is reported. Partial least squares (PLS-1) analysis of electronic absorption spectral data allowed the rapid and
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