13019AST
Astec® CHIROBIOTIC® R Chiral (5 μm) HPLC Columns
L × I.D. 15 cm × 2.1 mm, HPLC Column
Synonym(e):
CHIROBIOTIC R Chiral Chromatography Column
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About This Item
UNSPSC-Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Empfohlene Produkte
product name
Astec® Chirobiotic® R Chiral HPLC Column, 5 μm particle size, L × I.D. 15 cm × 2.1 mm
Materialien
stainless steel column
Qualitätsniveau
Beschreibung
HPLC column
Produktlinie
Astec®
Verpackung
pkg of 1 ea
Hersteller/Markenname
Astec®
Parameter
0-45 °C temperature
241 bar pressure (3500 psi)
Methode(n)
HPLC: suitable
LC/MS: suitable
L × ID
15 cm × 2.1 mm
Matrix
high-purity silica gel particle platform
fully porous particle
Aktive Matrixgruppe
ristocetin A glycopeptide phase
Partikelgröße
5 μm
Porengröße
100 Å
operating pH range
3.5-6.8
Trenntechnik
chiral
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Allgemeine Beschreibung
CHIROBIOTIC® R, based on the ristocetin A glycopeptide covalently bonded to high purity silica particles, has shown particular applicability to enantiomers of anionic compounds. Selectivity on CHIROBIOTIC® R strongly correlates to the organic modifier, favoring the alcohol-type mobile phases by a large margin.
CHIROBIOTIC FAQs
CHIROBIOTIC Reference Bibliography
Chiral Product Literature
- Bonded phase: Ristocetin A
- Operating pH range: 3.5 - 6.8
- Particle diameter: 5, 10 or 16 μm
- Pore size: 100 Å
CHIROBIOTIC FAQs
CHIROBIOTIC Reference Bibliography
Chiral Product Literature
Anwendung
- Sensitive determination of D-lactic acid and L-lactic acid in urine by high-performance liquid chromatography-tandem mass spectrometry.: This study demonstrates the application of the Astec CHIROBIOTIC R Chiral HPLC Column in the sensitive determination of D-lactic acid and L-lactic acid in urine samples using HPLC-MS/MS. This highlights its utility in clinical and biomedical research for the analysis of chiral molecules in biological fluids (Henry et al., 2012).
- New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase.: This research utilizes the Astec CHIROBIOTIC R Chiral HPLC Column to develop a method for the chiral separation and determination of warfarin enantiomers. It underscores the column′s application in pharmaceutical analysis, particularly in the study of chiral drug enantiomers (Malakova et al., 2009).
Rechtliche Hinweise
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
Analytische Säule
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Enzyme-catalyzed synthesis of (R)- and (S)-3-hydroxy-3-(10-alkyl-10H-phenothiazin-3-yl)propanoic acids
Brem, Jurgen, et al.
Tetrahedron Asymmetry, 21 (3), 365-373 (2010)
H Henry et al.
Biomedical chromatography : BMC, 26(4), 425-428 (2011-08-16)
D-lactic acid in urine originates mainly from bacterial production in the intestinal tract. Increased D-lactate excretion as observed in patients affected by short bowel syndrome or necrotizing enterocolitis reflects D-lactic overproduction. Therefore, there is a need for a reliable and
Sébastien Canneaux et al.
The journal of physical chemistry. A, 114(34), 9270-9288 (2010-08-03)
The rate constants of the reactions of iodine atoms with H(2), H(2)O, HI, and OH have been estimated using 39, 21, 13, and 39 different levels of theory, respectively, and have been compared to the available literature values over the
P Dehouck et al.
Journal of chromatography. A, 1010(1), 63-74 (2003-09-25)
Erythromycin is a mixture of macrolide antibiotics produced by Saccharopolyspora erythreas during fermentation. A new method for the analysis of erythromycin by liquid chromatography has previously been developed. It makes use of an Astec C18 polymeric column. After validation in
Ting Zhou et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1002, 218-227 (2015-09-06)
The chiral inversion has been a concerned issue during the research and development of a chiral drug. In this study, a sensitive chiral liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for determination of salbutamol enantiomers in human plasma and
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