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U2875
Uric acid sodium salt
Synonym(e):
2,6,8-Trihydroxypurine, Sodium acid urate
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About This Item
Lineare Formel:
C5H3N4O3Na
CAS-Nummer:
Molekulargewicht:
190.09
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41106305
PubChem Substanz-ID:
NACRES:
NA.51
Empfohlene Produkte
Biologische Quelle
microbial
synthetic
Qualitätsniveau
Assay
11.0-13.0% anhydrous basis (Sodium, ICP)
Form
powder
Löslichkeit
1 M NaOH: 25 mg/mL, clear, colorless to faintly yellow
SMILES String
[Na].O=C1NC(=O)C2=C(N1)NC(=O)N2
InChI
1S/C5H4N4O3.Na.H/c10-3-1-2(7-4(11)6-1)8-5(12)9-3;;/h(H4,6,7,8,9,10,11,12);;
InChIKey
IHMJZGFANDMEJM-UHFFFAOYSA-N
Verwandte Kategorien
Anwendung
Uric acid sodium salt has been used in isotonic solution of NaCl dose titration study. It has been used as a suspension in NaCl for intra-articular administration to experimental animals to induce synovitis.
Biochem./physiol. Wirkung
Sodium urate is the sodium salt of uric acid. In gout, it is observed in synovial fluid. Sodium urate has been shown to precipitate calcium oxalate from urine. It is also known to reverse the inhibitory effects of reactive oxygen and nitrogen metabolites on gelatinase A activity. Excess sodium urate in soft tissues results in a condition referred to as tophi.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Kim Gilbert et al.
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Dissolved urate salts out calcium oxalate in undiluted human urine in vitro: implications for calcium oxalate stone genesis
Grover PK, et al.
Chemistry & Biology, 10(3), 271-278 (2003)
Medical Biochemistry, 410-410 (2014)
Effects of reactive metabolites of oxygen and nitrogen on gelatinase A activity
Owens MW, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 273(2), L445-L450 (1997)
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