T7004

Thymidine 5′-monophosphat Dinatriumsalz Hydrat

≥99%

• Synonym(e): 5′-Thymidylsäure Dinatriumsalz, 5′-dTMP-Na₂, TMP
• Empirische Formel (Hill-System): C₁₀H₁₃N₂Na₂O₈P · xH₂O
• CAS-Nummer: 33430-62-5
• Molekulargewicht: 366.17 (anhydrous basis)
• Beilstein: 4086927
• EG-Nummer: 251-518-0
• MDL-Nummer: MFCD09039259
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 329826857
• NACRES: NA.51

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥99%
• Lagertemp.: −20°C
• SMILES String: O.[Na+].[Na+].CC1=CN([C@H]2C[C@H](O)[C@@H](COP([O-])([O-])=O)O2)C(=O)NC1=O
• InChI: 1S/C10H15N2O8P.2Na.H2O/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18;;;/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t6-,7+,8+;;;/m0.../s1
• InChIKey: KCOPAVKVHIWPKB-SPSULGLQSA-L

Beschreibung

Allgemeine Beschreibung

Thymidine 5′-monophosphate de novo synthesis from deoxyuridine monophosphate (dUMP) is catalyzed by the enzyme thymidylate synthase.

Anwendung

Thymidine 5′-monophosphate disodium salt hydrate has been used as a standard for the quantification of metabolites from plasma and tumor interstitial fluid using liquid chromatography-mass spectrometry analysis (LC/MS). It has also been used as a single deoxy-mononucleotide to test its effect on the cell growth of human malignant intestinal CaCo-2 cells and normal rat intestinal cell line IEC-6 cells.

Thymidine 5′-monophosphate disodium salt hydrate has been used as a standard solution.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)