SML3589

ITD-1

≥98% (HPLC)

• Synonym(e): 4-[1,1′-Biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid ethyl ester, Inducer of type II TGF-b receptor (TGFBR2) degradation-1
• Empirische Formel (Hill-System): C₂₇H₂₉NO₃
• CAS-Nummer: 1099644-42-4
• Molekulargewicht: 415.52
• MDL-Nummer: MFCD28133391
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear (Warmed)
• Lagertemp.: 2-8°C
• SMILES String: O=C(CC(C)(C)C1)C2=C1NC(C)=C(C(OCC)=O)C2C(C=C3)=CC=C3C4=CC=CC=C4
• InChI: 1S/C27H29NO3/c1-5-31-26(30)23-17(2)28-21-15-27(3,4)16-22(29)25(21)24(23)20-13-11-19(12-14-20)18-9-7-6-8-10-18/h6-14,24,28H,5,15-16H2,1-4H3
• InChIKey: ULFUJLFTRWWLPO-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

ITD-1 is a selective TGF-ß pathway inhibitor that induces selective proteasomal degradation of type II TGF-b receptor (TGFBR2). ITD-1 stimulates embryonic stem cells to differentiate into cardiomyocytes.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable